ID A0A3Q2VK99_HAPBU Unreviewed; 883 AA.
AC A0A3Q2VK99;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Adhesion G protein-coupled receptor D1 {ECO:0000313|Ensembl:ENSHBUP00000012257.1};
GN Name=ADGRD1 {ECO:0000313|Ensembl:ENSHBUP00000012257.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000012257.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000012257.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q2VK99; -.
DR STRING; 8153.ENSHBUP00000012257; -.
DR Ensembl; ENSHBUT00000019637.1; ENSHBUP00000012257.1; ENSHBUG00000013958.1.
DR GeneTree; ENSGT00940000159783; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF216; ADHESION G-PROTEIN COUPLED RECEPTOR D1; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 578..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 682..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 721..747
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..789
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 795..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 575..819
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 883 AA; 98071 MW; FBA33DC2964C9679 CRC64;
MLYFAETMAF CLRIRIFTAF VSFIKVYAQV AQAQKHPGLE VLDTASHYWP LDAVEGIHEL
WDHNGNRSGY INGSNINIVE GMVNKGIFLN GDNGGTFLHF GNYQNTCISD PNLCGPEGIT
FSFFWKNHES ASRFAVASGG KVISNGFSVY TNPLGGYVEF YTRSNKHRWR ANIDVPGPYW
THILFTWTKK DGLKVYINAT LTAENKNGSI SEETYGDPYP DLVIGTANNK GYSHYVTGAF
DEFVIWERAL SPENISLYYN ATIAWDMVSK TTPRISKEVI STTPMARAAD MSPPVISSLQ
EELRPTDFLP VQSFLKTLPN GTISRDTANN LTQGLLKSVE EVLSFPGLTE QSTPVVSGLV
KTVDRVMEHV VTNLEDSPNS LISLDGTSFV ADYSLMKLPQ NFELSHYRFP TEGKSYISVP
GEAFAMESQT TIVGLFYHNM HSYYKEISPV KTRINEAADY KDHKIHVASC LISLKVEPLP
ALSVNLSGAP LIKIVLTHVL TKEQQDQVQN QSNKVFLYCA FLDYSSKEGV WSNKGCVRAH
GNMTYSVCLC NHLTNFAILM QVVPLKISTG HKVALSTIGY VGCSISIFCL AITLVTFAVL
SSVSTIRNQR YHIHANLSFA ILVAEILLLI SARFDPGTLP CKVMAVLLHF FFLSAFAWML
VEGLHLYSMV VKVFGSEDSK HFYYYGIGWG SPFLICVVSM TSALDSYGKV DNCWLSLQNG
AIWAFVAPAL FVIVVNIGIL ISVTRIISRI SGENYKVHGD ANAVKLTIKA VAVLLPILGI
SWIFGVLVVN TQSLPFLYIF AVFNSLQGFF VFLFHCLLNS EVRAAFKHKT KVWSLTSSSI
RNINVKPFNS DIMNGHKEGV TPTKMNTWDK STNSANRIDL SAV
//
