ID   A0A3Q2VKL3_HAPBU        Unreviewed;      1152 AA.
AC   A0A3Q2VKL3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=MKL/myocardin-like protein 1 {ECO:0000313|Ensembl:ENSHBUP00000012030.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000012030.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000012030.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q2VKL3; -.
DR   Ensembl; ENSHBUT00000019374.1; ENSHBUP00000012030.1; ENSHBUG00000013729.1.
DR   GeneTree; ENSGT00950000182979; -.
DR   OMA; LPGHNPV; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   Gene3D; 6.10.140.2040; -; 1.
DR   Gene3D; 6.10.150.10; -; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   InterPro; IPR043451; Myocardin-like.
DR   InterPro; IPR004018; RPEL_repeat.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   PANTHER; PTHR22793:SF6; MYOCARDIN-RELATED TRANSCRIPTION FACTOR A; 1.
DR   PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR   Pfam; PF02755; RPEL; 2.
DR   Pfam; PF02037; SAP; 1.
DR   SMART; SM00707; RPEL; 3.
DR   SMART; SM00513; SAP; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS51073; RPEL; 3.
DR   PROSITE; PS50800; SAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REPEAT          43..68
FT                   /note="RPEL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT   REPEAT          87..112
FT                   /note="RPEL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT   REPEAT          125..150
FT                   /note="RPEL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT   DOMAIN          385..419
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   REGION          163..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          327..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          420..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          843..864
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          892..958
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          971..993
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..246
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..353
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..436
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        914..928
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        979..993
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1152 AA;  128063 MW;  7B48F68171D2E9E1 CRC64;
     MLEHPPCVRI DPAPFRPQPI RCNMDKPDMR FELERQACQS LRQVLQLKLQ QRRSREELVS
     QGIMPPLKTS AAFHEQRRSL ERARTEDYLK RKIRSRPEKS ELIRMHILEE PFLPVKQLKK
     ACLAVDLNDK IAQRPGPMEL IHKNILPVHS SIKQAFIETQ FQRASGENSS FDEDTNDSLS
     PEQSTSVSEE GCSLGLGPLP TPKETLTGHG IPSPTQVPPT APSGSPISLK LTNETGASSL
     LRTGANKPQP KPNCDRSGLR HKKTKDKPKI KKLKYHQYIP PDQKGDKEPP PHLDSSYAKI
     LQQQQLFLQL QILSQQQQRY HTILPAPTKS QTAQQPSSSS KSMHTSSSPP RPAGAPLNFS
     KHFVHTCLSS VPLGGTKPVS LPPNLDEMKV AELKSELKLR NLPVSGTKND LIERLRTYQE
     LSRGSDTTSS PTAGCTTGPG AEGAGKSSKS AAFIITSNDT RIEMSSPLNQ LSLQPSSVAQ
     LSTNIKEEPR CSTPAPCQYS LKSASLQRRS SVSSGVPATT STVPVPSVDK DRLLQEKDKQ
     IEVLTRMLWQ KQRLVEVLKM QLENGDRGKA PEPISPLGVK EEPLDEPDVA FSMDFDQFPS
     QKSPISQEMD ITKVIVKQEV IEEEEVKPEK NFQFPITHGL PQSSTQTQEE QLAQQHTIQK
     VLLQQQQHII QNQTLENQHD LQKLCQQRKK KSQNQQKQLL LQSQQQHQQS KHVQQMQLKQ
     QLLLKQQKSH MLPQQMKTKQ QTKQLQQIQI QTKIQLKQQQ VPKQQVKQQQ QPSKVPQAYL
     KQQSGSSASF SMDHLKIDST PTLVTDTNGN HFLIALTNHL TGNKIKDPAE GKATNHITLQ
     RLQSTPAKRP GHNPVKLTRA DSKAQQSMQV KFVKKHTKNG VLQVSVEKPH QGTAQCLSAP
     PSLQPFFRDQ EPAPSGKNTP SSPSQGEVCP NLEDLFSPVS PASVQTAASS PDGKDTDHED
     DFIDIILQRG ETSCKPPPDL SLNRLNQDSS ACSLPPSPLQ MLLPPSPPIP PCCGTPHPDP
     SLQPELQTVA DTTGQKQHLS HAESGRLEDF LESTTGRPLL GVEPGGLLSL IDDLHNQMLC
     TSSILNHPLS PMDTSDTASW EQGLDSMDWL NLTTERDREE ESPSLALQTP PSVFSTDFLD
     SSDLHIHSEF SL
//