ID   A0A3Q2VNU3_HAPBU        Unreviewed;       343 AA.
AC   A0A3Q2VNU3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Major histocompatibility complex class I-related gene protein-like {ECO:0000313|Ensembl:ENSHBUP00000013792.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000013792.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000013792.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   AlphaFoldDB; A0A3Q2VNU3; -.
DR   STRING; 8153.ENSHBUP00000013792; -.
DR   Ensembl; ENSHBUT00000033096.1; ENSHBUP00000013792.1; ENSHBUG00000015624.1.
DR   GeneTree; ENSGT01100000263475; -.
DR   OMA; NEINRCE; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF237; MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        307..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          182..289
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   343 AA;  39611 MW;  0E206F84C5E67F20 CRC64;
     FKSCFLFECL LIQSLPNFTV KHSLKYFFTE TPGAQSIPEY VVVAFVDEVP IGDFNSVRGA
     DLKKDWIKFF EDHPQHLEWC ILQSVDRHHF LKATIETLRQ QLNQTEGVHI LQKLDGCEWD
     DETGEINGFN QYGYDGEDFL ALDLQTLTWI TAKPQAAITK MKWDAQKVRV EENKKFFGDQ
     CPEFLKEYLR YGRRFLQKTI LPSVSLLQKT PFSPISCHAT GFYPDRGLMF WRKDGEELHE
     GVDPGEILPN NDETFQMSID LKLSSFTPED WERYDCVFQL SAVKEHIVTK LDKTMIRTNW
     EKPADTVTFI SAAVVVLTVT IITGVAFVAY KKKKGEKSQC GKY
//