ID A0A3Q2VUD2_HAPBU Unreviewed; 422 AA.
AC A0A3Q2VUD2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSHBUP00000012053.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000012053.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000012053.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005941984.1; XM_005941922.1.
DR AlphaFoldDB; A0A3Q2VUD2; -.
DR Ensembl; ENSHBUT00000032373.1; ENSHBUP00000012053.1; ENSHBUG00000013749.1.
DR GeneID; 102302491; -.
DR CTD; 10379; -.
DR GeneTree; ENSGT00940000166207; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF26; INTERFERON REGULATORY FACTOR 9; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 9..116
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 123..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 47780 MW; 41BDD1DE8A84ECA2 CRC64;
MAAGRMRSTR RLRSWIVEQV SSGKYPGLVW DDEAKTMFRI PWKHAGKQDF RKDEDAAIFK
AWAEFKGKLT DGGQDNPAAW KTRLRCALNK SPEFKEVMDR AQLDISEPYK VYRLVPISEQ
GVVVPEKKSR EKASRRSKRR RSDSDSDAAS DDKQIKREEA TSQLYVEESP VQTEEPTQCP
TFIQTDSVDE IRLDVRIEES VTAPVGAQDS FSVAVYYLGQ QVLKRQIQGT DVRIMYLPSS
PIPPTPLVLK ARFPRIPLPE PPSTLPAGPE LQALFTLLPF MEKGVVLTST PQGVYGKRFC
QGRVFWTGPH TTMPDLHKME RNTEPVLLFN KEIFKQQLDY FRTNGGEPPQ CGFTLCFGEE
LSDSEDPFQK LIIVQITLPW EEQQVQNAQS IFESITILQS LASQSPLGEI TLNLVTVPSP
TN
//
