ID   A0A3Q2VW34_HAPBU        Unreviewed;       479 AA.
AC   A0A3Q2VW34;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Vacuolar fusion protein MON1 homolog {ECO:0000256|RuleBase:RU367048};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000012733.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000012733.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Plays an important role in membrane trafficking through the
CC       secretory apparatus. {ECO:0000256|RuleBase:RU367048}.
CC   -!- SIMILARITY: Belongs to the MON1/SAND family.
CC       {ECO:0000256|ARBA:ARBA00008968, ECO:0000256|RuleBase:RU367048}.
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DR   AlphaFoldDB; A0A3Q2VW34; -.
DR   Ensembl; ENSHBUT00000020236.1; ENSHBUP00000012733.1; ENSHBUG00000014446.1.
DR   GeneTree; ENSGT00390000006665; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR   InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR   InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR   InterPro; IPR004353; Mon1.
DR   PANTHER; PTHR13027; SAND PROTEIN-RELATED; 1.
DR   PANTHER; PTHR13027:SF14; VACUOLAR FUSION PROTEIN MON1 HOMOLOG A; 1.
DR   Pfam; PF19036; Fuz_longin_1; 1.
DR   Pfam; PF19037; Fuz_longin_2; 1.
DR   Pfam; PF19038; Fuz_longin_3; 1.
DR   PRINTS; PR01546; YEAST73DUF.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          121..243
FT                   /note="FUZ/MON1/HPS1 first Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19036"
FT   DOMAIN          281..380
FT                   /note="FUZ/MON1/HPS1 second Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19037"
FT   DOMAIN          409..474
FT                   /note="FUZ/MON1/HPS1 third Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19038"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          63..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          90..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..113
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  53939 MW;  12FC39D24BFD81A6 CRC64;
     MEGEAQKATA SWESGTLAPV DRLRSVRADS PIPGLVEGTE PGAGQKSAMF IHAHSFEDLT
     AEAEEEALRT ADSGKSEEQH EEGLKALVAE QNIDEQHSND LSDSRTKEED VSSEAWRSHK
     KHVFVLSEAG KPIYTRYGTE EALSSTMGVM MALVSFVEAE KNIIRSIHAD GCKVVFLTKS
     PLVLVGVSRT CQSDKEMLRE LQYIYYQIVS LLTLTQLNHI FQHKQNYDLR RLLAGSEYLT
     DNLLIRLERD PGLLLSAVTC LPLPSSARDV VSSSLQAAKS KNLVFSILLA GDRLVTLVRK
     KDQFLHHIDL HLVFNLVGSS SSFREGEGWT PICLPKFNTA GFFHAHISYL EPASQLCLIL
     VSTEREDFFN MSDCKQKFME RLSKRSAYQA LKEAVKCPSY SVVQVGIPEL RHFLYKSKSS
     GLYTSPEFPM VYQSDGEQER LLSLYQELHS CLHHPTRPLR YYYRCRETEN LLAQVSLVL
//