ID   A0A3Q2VXS4_HAPBU        Unreviewed;      1318 AA.
AC   A0A3Q2VXS4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Tubulin--tyrosine ligase-like protein 5 {ECO:0000256|ARBA:ARBA00041448};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000016700.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000016700.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-glutamate + L-glutamyl-[protein] = ADP + gamma-L-
CC         glutamyl-L-glutamyl-[protein] + H(+) + phosphate;
CC         Xref=Rhea:RHEA:60144, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:15517,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29973, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:143622,
CC         ChEBI:CHEBI:456216; Evidence={ECO:0000256|ARBA:ARBA00036640};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60145;
CC         Evidence={ECO:0000256|ARBA:ARBA00036640};
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DR   STRING; 8153.ENSHBUP00000016700; -.
DR   Ensembl; ENSHBUT00000025294.1; ENSHBUP00000016700.1; ENSHBUG00000018667.1.
DR   GeneTree; ENSGT00940000162910; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   PANTHER; PTHR12241:SF145; TUBULIN POLYGLUTAMYLASE TTLL5; 1.
DR   Pfam; PF03133; TTL; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS51221; TTL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          399..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          894..930
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1168..1191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..432
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        433..447
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        908..930
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1318 AA;  147464 MW;  AF2645A98557F106 CRC64;
     MPAVIRDKED SESSSEDEQE DHPCISWGSL SKTIPILLFF PEAVVSKDGS ISSVGERYNM
     AFKIVRTESR LVREILTNHG FHEVHPNSND FNLMWTGSHL KPYVLRSLQD FQKVNHFPRS
     HELTRKDRLY KNIQRMQQTH GFKNFHIVPQ TFVLPAEYQE FCNCFAKDKG PWIIKPVASS
     RGRGIYLVSN PNQISMTENI LVSRYINNPL LIDGFKFDVR LYVLVTSYDP LLIYVYEEGL
     ARFATVKYDR TSKNIKNTFM HLTNYSVNKK SSDYVSCDDP EVEDYGNKWS MSAVLRYLKQ
     EGKDTTSLMK QVEDLIVKAV LSAELQIATA CKTFVPHKTN CFELYGFDVL IDSNLKPWLL
     EVNLSPSLAC DAPLDLKIKA SMIADMFSLV GFVCQDPLSR QPRSDQRTQK LFSAHPATTH
     SRVRQRPTST NISETEDLKD KRGAKHGQGD STLNLTVEEI RVLRRIKEEY ERRGGFIRIF
     PTADTWELYG GYLESKTSMN FVLANRLFHG RNVNGNVQLQ VDVVHGCHVV QYERKLLSLE
     ARKRRQRHLT HGSAARKKKS GKESKASLTE NSSQEGEECA QEEVKQVLEP VSHKALVAEQ
     RKQVATPLER CHSKAQSSSE AAVHNASPTV NLLNILQQGW ELSKMQARIA FSSYLQRVQQ
     RLLAESRDNT ISAWPDNGND QMELVIRFLR KAASNLQQDI KVVLPSRQLP LQDRRRILSH
     QLGEFIHCYN KETEHMVKKQ EISKEERCVN PKVFQEYISA ASENDLEEVL TFYTQKNKSA
     TVFLGTKVRG IKKDVREANA SRDSGNCDNS KSLAVEADSE LSLLTGKVSS DSDNKATDGQ
     PSFCLLTEDI QAEVRMVKTQ PEVQSTQHRS SFPVTLDCVH NHLQHCSPAS LPLHCPPPPP
     PPQPPSYAQS LAKSHLCHSE SLSDPPAYTS AHVVTQPPRV LWTAAPTGSN AATTGPSTQV
     LRRIQSFTSS MAGSAAASSV PSATHIYSQK LSRPTSAGQV IRRSTSSKLK SNSVGAFREL
     STLTAQAQSN QQAFISALQK LADKQVAHHY ASSSHINLLT QHLTNLNLAN KMLSRESFTL
     NPKAATIQGP VRAVHPETDL PNSTGHRPLK EEDWQMHNDY SLVRGVTPKQ HYQPTQGSYQ
     LQFAIQQLQQ QRLKAHHQFL DQTRCGHQAQ FPDQTPHSQA LTKSSSCPPS SFHTLPNQSH
     GLSHVQTCVS PALAPKPPSG AREGQVRRTT AKRLVKQMSS ESSASGTVAS SKQVVYEAIC
     GKTGLLREIQ LSPSSPHLWT LLIVEMNGQF THLVELNPLL VSPGAGVGDP QGSKLSPE
//