ID A0A3Q2VZ44_HAPBU Unreviewed; 495 AA.
AC A0A3Q2VZ44;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=OXA1L mitochondrial inner membrane protein {ECO:0000313|Ensembl:ENSHBUP00000017531.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000017531.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000017531.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014190211.1; XM_014334725.1.
DR AlphaFoldDB; A0A3Q2VZ44; -.
DR STRING; 8153.ENSHBUP00000017531; -.
DR Ensembl; ENSHBUT00000026349.1; ENSHBUP00000017531.1; ENSHBUG00000019569.1.
DR GeneID; 102314053; -.
DR CTD; 5018; -.
DR GeneTree; ENSGT00530000063506; -.
DR OMA; GWKNAQT; -.
DR OrthoDB; 5395681at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR CDD; cd20069; 5TM_Oxa1-like; 1.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF66; MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 198..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 200..393
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
FT REGION 461..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 54361 MW; 55B951A06BC658D7 CRC64;
MAAVRSGLTP VCLTRCFLRQ TGKPSRGGHP LSDIWSHRLI QRSHLHTVFE CRSPATRALL
GRRHHDKFLW VNAVAVRHNS SQIPPDGGSI AVPVTETLNS PPVLESVTQP VTEQILGGTV
SSVLPAAESS VLPLVSADPA PVLTQPVSEQ VADVAPTAVE VLQAVAGEPR LAELGLAGHT
PVGLVQNMLE FIHMDLGLPW WGAIVVATVL ARLAVFPVIV KGQREAAKLN NVLPEMTKLT
NRMNEAKQSG NKFEFSKAYS DLNLFQKNHD VNPLRGFLIP LVQTPVFISF FIALRKMAYL
PVPSMQTGGM LWFADLTASD PFYILPLAVT GTMFFILELG AESGIDNPNL RAMKTVFRIM
PLVIFPLTIN FPTAVFTYWL TSNCFSLCQV ALLRHPLIRK KLKIPERIKH PASALPQSDG
LIESMKKGWK NAQLAHQLEE RERRIKNHLD LAAKGPLRQT FTHNPLEQKP PIAAAASAKD
KSAGSKTRPW KDTIG
//
