ID A0A3Q2W092_HAPBU Unreviewed; 437 AA.
AC A0A3Q2W092;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=T-box transcription factor TBX20 {ECO:0000256|ARBA:ARBA00044102};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000014353.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000014353.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_005929497.1; XM_005929435.2.
DR AlphaFoldDB; A0A3Q2W092; -.
DR STRING; 8153.ENSHBUP00000014353; -.
DR Ensembl; ENSHBUT00000022327.1; ENSHBUP00000014353.1; ENSHBUG00000000760.1.
DR GeneID; 102304580; -.
DR CTD; 57057; -.
DR GeneTree; ENSGT00940000158741; -.
DR OMA; EDGHTTH; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR GO; GO:0035844; P:cloaca development; IEA:Ensembl.
DR GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0003313; P:heart rudiment development; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0060043; P:regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR CDD; cd20193; T-box_TBX20-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF190; T-BOX TRANSCRIPTION FACTOR TBX20; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 98..282
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
SQ SEQUENCE 437 AA; 48672 MW; 84F17A47F1934326 CRC64;
MEYTSSPKPQ LSSRANAFSI AALMSSGKPN KDKEAEENTI KPLEQFVEKS SCNQQSLADL
SSLDGHGDFS APAVCTEPLI PTNPGIPSEE MAKISCSLET KELWDKFHEL GTEMIITKSG
RRMFPTIRVS FSGVDQDSKY IVLMDIVPVD NKRYRYAYHR SSWLVAGKAD PPLPARLYVH
PDSPFTGEQL MKQMVSFEKV KLTNNELDQH GHIILNSMHK YQPRVHIIKK KDHTASLLNL
KSEEFRTFVF IETVFTAVTA YQNQLITKLK IDSNPFAKGF RDSSRLTDME RESVENLIHK
HSYARSPIRT YAGDEENLSE DGHASHTRGS AFTASDNLSL SSWVTTTSGF SGFQHPQSLS
AMGTGTAPLP HPIQGSLPPY SRLGMPLTPT ALAGTMQGSG PSFPTFHMPR YHHYFQQGPY
AAIQGLRHSS TVMTPFV
//
