ID A0A3Q2W1A1_HAPBU Unreviewed; 618 AA.
AC A0A3Q2W1A1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Lymphocyte cytosolic protein 1 {ECO:0000313|Ensembl:ENSHBUP00000018371.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000018371.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000018371.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005943495.1; XM_005943433.1.
DR AlphaFoldDB; A0A3Q2W1A1; -.
DR Ensembl; ENSHBUT00000027395.1; ENSHBUP00000018371.1; ENSHBUG00000020508.1.
DR GeneID; 102293255; -.
DR CTD; 3936; -.
DR GeneTree; ENSGT00950000183097; -.
DR OMA; WQLMRKN; -.
DR OrthoDB; 5475188at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21333; CH_PLS2_rpt4; 1.
DR CDD; cd21292; CH_PLS_rpt1; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR PANTHER; PTHR19961:SF35; PLASTIN-2; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13405; EF-hand_6; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 2.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 9..44
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 113..229
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 257..368
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 387..496
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 508..616
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 618 AA; 69395 MW; C720F9265FD608F6 CRC64;
MAAPPITAEE LEDLREAFTK IDVDNDGIIS KDELDAVLKA ANLSLPGYRV REMIQELSKS
SEELNFDKFT EIVHGLKSAE VAKTFKKAIT KKEGICNVAG TSEQTGTQHS YSEEEKVAFV
NWINKALEKD PDCKHVLPMD PNTNDLFTAM GDGIVLCKMI NLSVADTIDE RTINKKKLTP
FTIQENLNLA LNSASAIGCH VVNIGAEDLK EGRQHLVLGL LWQVIKIGLF ADIELSRNEA
LIALLRDGES LEDLMKLSPE ELLLRWANYH LEEAGCGKIN NFNNDIKDSK AYYNLLNQVA
PKGDEEGIPP IAVDMSGLRE KDDLKRAELM LDQADRLGCR QFVMPTDVVR GNPKLNLAFV
ANLFNKYPAL KKPENQDIDW SSIEGETREE RTFRNWMNSL GVNPRVNHLY ADIDDALVIF
QLYEKIKVPV DWDRVNKPPY PKLSSNMKKL ENCNYAVELG KKEAKFSLVG IAGQDLNEGN
RTLTLALLWQ LMRRYTLNIL EDLGDGQKVI DETIVSWVND NLTRAGKSTI SSFKDRSIST
SMPVLDLIDT IQPGSIRYDL LKTEDLTDEE KLNNAKYAIS MARKIGARVY ALPEDLVEVK
PKMVMTVFAC LMARGLRA
//
