ID   A0A3Q2W241_HAPBU        Unreviewed;       795 AA.
AC   A0A3Q2W241;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Nuclear cap binding protein subunit 1 {ECO:0000313|Ensembl:ENSHBUP00000018691.1};
GN   Name=NCBP1 {ECO:0000313|Ensembl:ENSHBUP00000018691.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000018691.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000018691.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NCBP1 family.
CC       {ECO:0000256|ARBA:ARBA00007413}.
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DR   RefSeq; XP_005924119.1; XM_005924057.2.
DR   AlphaFoldDB; A0A3Q2W241; -.
DR   SMR; A0A3Q2W241; -.
DR   STRING; 8153.ENSHBUP00000018691; -.
DR   Ensembl; ENSHBUT00000027816.1; ENSHBUP00000018691.1; ENSHBUG00000020843.1.
DR   GeneID; 102302231; -.
DR   GeneTree; ENSGT00390000001733; -.
DR   OMA; CAAEGLM; -.
DR   OrthoDB; 5477544at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027159; CBP80.
DR   InterPro; IPR015172; MIF4G-like_typ-1.
DR   InterPro; IPR015174; MIF4G-like_typ-2.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR   PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   Pfam; PF09088; MIF4G_like; 1.
DR   Pfam; PF09090; MIF4G_like_2; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   3: Inferred from homology;
KW   mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Transport {ECO:0000256|ARBA:ARBA00022816}.
FT   DOMAIN          28..240
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          664..702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..680
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        681..695
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  92307 MW;  2ED76A77F5DD3527 CRC64;
     MSRRRHSDEN DGGQAHKRRR TSEPIEIEDR LESLICRVGE KSTSSLESNL EGLAGVLEAD
     LPNYKSKILR ILCAVARLLP EKLTVYTTLV GLLNARNYNF GGEFVEAMIR QLKETLKNNL
     YSEAVYLVRF LSDLVNCHVI AAPSMVAMFE NFVSVTQEED VPQVRSDWFV YVVLSCLPWV
     GKELYEKKDV EMDRLLSQIE GYLKRRVKTH VPMLQVWTAD KPHPQEEYLD CLWAQIQKLK
     KDRWQERHIL RPYIAFDSVL CEALQHNLPP FTPPGHMPDA QYPMPRVIFR VFDYTDAPEG
     PVMPGSHSVE RFVIEENLHC IIKTHWKERK TCAAQLLSYP GKNKIPLNYH IVEVIFGELF
     QLPSPPHIDV MYTTLLIELC KLQPGSLPQV LAQATEMLYM RLDTMNTTCI DRLINWFSHH
     LSNFQFRWSW DDWSDCLTVD LEKPKPKFVK EVLEKCMRLS YHQRIVDIVP PTFSALIPAD
     PIFTYKYPDE SASSLPGYPM SITVSNAIKN RASNEEILTV LKEVPNPNQE DDDDEGESFN
     PLKIDVFLQT LLNLAAKSFS HSFSALGKFH EILKTLANSD EGKLHLLKVL YEVWRNHPQM
     IAVLVDKLIR TQVVDCAAVA NWLFSQDMAH EFTRLFIWEI LHSTIRKMNK HVQKIQKELE
     EAKDKLEKQQ HKRRDSGDDE DMDKNSEDEE GQLEEQIERL QEKVESAQSE QKNLFLVIFQ
     RFIMLLTEHL VRCETGSVDI STPWYKNGIE RLQQIFLMHH ATIQQYMGTL ENLLFTAELD
     HHILAVYQQF CALQL
//