ID   A0A3Q2W738_HAPBU        Unreviewed;       481 AA.
AC   A0A3Q2W738;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSHBUP00000021338.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000021338.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000021338.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00010371}.
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DR   RefSeq; XP_005920463.1; XM_005920401.2.
DR   AlphaFoldDB; A0A3Q2W738; -.
DR   STRING; 8153.ENSHBUP00000021338; -.
DR   Ensembl; ENSHBUT00000036338.1; ENSHBUP00000021338.1; ENSHBUG00000023649.1.
DR   GeneID; 102300475; -.
DR   CTD; 10493; -.
DR   GeneTree; ENSGT00940000157579; -.
DR   OMA; ACAINRH; -.
DR   OrthoDB; 6736at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08275; MDR3; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR44054:SF1; SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG; 1.
DR   PANTHER; PTHR44054; SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          71..398
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   REGION          1..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..481
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  53541 MW;  AEAD49DDA8CA1FE7 CRC64;
     MSGEDAPAQQ QNAVDQKQET KPTEEPKTEP PKTESPPAAA AEAAATPAAT TEKVPEEETF
     TYRALVLTGY GGYDKVKLQV KKGKPTLKAG EVLVRVKACG LNFADLMARQ GLYDRLPSPP
     VTPGMECSGV VEAVGEEVTD RKVGDKVMVL NRFGLWQEVA VVPANHTFLI PEGMSFEEAA
     ALPVNYITAY MMLFDFGNLR PNQSVLVHAA AGGVGIAATQ LCKTVKDVTV FGTASASKHE
     TITQGGVTHA IDYRTKDYVE EVRKISPKGM DIILDPLGGS DTHKAYNLLK PMGKLITYGA
     ANMLAGQKKN LLAVAKNWYH QFSIHTLSLI QGNKSVCGFH LGYLDGETEL ITEAMNTILD
     FYKDGKIKPR IDSTWHLEQV GDAMRKMQER NNIGKVILTT EPMPEEEKKE ETKKEDKKED
     KKKEDKKKDD KKKDDAKKEE KKEEKKDDKK DDKKDDKKKE EPKKEEKKEE EKKEEPKKEE
     K
//