ID   A0A3Q2WAY0_HAPBU        Unreviewed;       816 AA.
AC   A0A3Q2WAY0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=EMAP like 2 {ECO:0000313|Ensembl:ENSHBUP00000022321.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000022321.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000022321.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC       {ECO:0000256|ARBA:ARBA00006489}.
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DR   RefSeq; XP_005932651.1; XM_005932589.1.
DR   AlphaFoldDB; A0A3Q2WAY0; -.
DR   STRING; 8153.ENSHBUP00000022321; -.
DR   Ensembl; ENSHBUT00000013947.1; ENSHBUP00000022321.1; ENSHBUG00000002552.1.
DR   GeneID; 102294481; -.
DR   CTD; 24139; -.
DR   GeneTree; ENSGT00940000153887; -.
DR   OrthoDB; 2959353at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR049040; RMC1_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF03451; HELP; 1.
DR   Pfam; PF21029; RMC1_N; 1.
DR   Pfam; PF00400; WD40; 5.
DR   SMART; SM00320; WD40; 11.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          189..259
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REPEAT          457..489
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          540..581
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          608..693
FT                   /note="Regulator of MON1-CCZ1 complex N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21029"
FT   REPEAT          669..710
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          781..816
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          73..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          33..67
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        134..159
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..177
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   816 AA;  89826 MW;  31BD22BE541DAE9B CRC64;
     MSERVASCGS LYDSTNLLLQ YCNNDDTVSA SSNMDMEDRV SHLEQRLQLQ EDEIQLLKAA
     LADALRRLGY CEEQSQGKQP AGVHAGRRSL ATTAAAPPTK VRQLLQALPS RPLSNGYIQQ
     KRLLSSPSSP KKEVLQSIKR KSMSTERLTL VRREMGAESR SRTTSSSSSS GGKSKSKECT
     FNAEDSYVRM FLRGRPVTMH VPDQQKGTYS LDQKVALPDH KLKLQWVYGY RGRDCRSNLY
     LLPTGEIVYF NASVVVLYNT EEQQQRHYLG HNDDVKCLSV HPDMVTIATG QVAGNSKDGK
     LLAPHVRVWD SVSLNTLHVL GTGVFDRAVT CVAFSKSNGG TFLCAVDDAN DHILSVWNWQ
     KEKQLAEVKC SNDSVLAAVF HPMDTNLIVT CGKSHINFWT MEGNTLTKRQ GLFEKHEKPK
     YVLCVAFAEN GDAITGDSSG NLYIWAKGGT RISQVVSAAH EGGIFSVCVL KDGTMVSGGG
     KDRKVVLWDH DYRKKATMEV GESFGPVRAL AEGKPGELFV GTTKNAIIRA AFPDTLTPIV
     QGHTDELWGL DIHPTMEQFV TCSQDKQVHL WDAHSHQPLW SKTIEDPGRS AGFHPSGAVL
     AVGTMTGKWL VLDTDTRDLV SMHTDGNEII SNVKYSPDGN FLAVASHDNF VYIYAVTENG
     RKYSRVGKCT GHSSFVTHVD WSKNSQYLVT NSGDYEILFW EASSGKHVTN MDTVRNLEWA
     TSTCTLSFNT FGIWPDGADG TDINAACRSH DGSLLASADD FGKVHLFSFP CSQPRAPSQE
     YGGHSSHVTN VAFLHDDSHL ISTGGKDTSI LQWVVA
//