ID A0A3Q2WC55_HAPBU Unreviewed; 586 AA.
AC A0A3Q2WC55;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000023398.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000023398.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A3Q2WC55; -.
DR Ensembl; ENSHBUT00000011241.1; ENSHBUP00000023398.1; ENSHBUG00000006779.1.
DR GeneTree; ENSGT00940000164201; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT DOMAIN 30..289
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 500..586
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 586 AA; 66465 MW; 7C10B8A9EC59519D CRC64;
MSTLNQQYEE KVRPCIDLID SLRSLGVEKD LALPAIAVIG DQSSGKSSVL EALSGVALPR
GSGIVTRCPL ELKMKRKKEG EEWTGRISYQ GHEEEIEDPT TVDKKIEEAQ NEMAGVGVGI
SDELISLAIA SPEVPDLTLI DLPGIARVAV KGQPENIGDQ IKRLIQKFIT KQETISLVVV
PCNVDIATTE ALKMAQQVDP EGERTLGILT KPDLVDKGTE ENVLEIVHNE VIHLNKGYMI
VRCRGDFFSD FACVTLPFDL QRSLPRLEEQ IEDKLAQTQA ELDRYGNGPP SGMAERIIFL
IDKVTAFTQD AINLTSGEEL NCGENLNVFS TLRREFGKWN AHLDRSGQNF NRKIEKEVEV
YEDKYRGREL PGFINYKTFE VMVKEQIKQL EEPAVKKLKD IADAIKRVFL QLAQRSFTGF
PNLIKTAKAK IEAIKQDKEA TAESMLRTQF KMELLVYSQD RTYSNSLTES KQEDDEEEVE
HNHRGKLRTP VYTKDNHATL QELMLHLKSY YKIAGQRLAD QIPLVIRYHM LQEAAIQLQR
EMLQMLQDKE KLEFLLKEDS DIGTKRAALQ NRVTRLMKAR AYLVEF
//
