ID A0A3Q2WDT8_HAPBU Unreviewed; 1362 AA.
AC A0A3Q2WDT8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Astrotactin 2 {ECO:0000313|Ensembl:ENSHBUP00000019824.1};
GN Name=ASTN2 {ECO:0000313|Ensembl:ENSHBUP00000019824.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000019824.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000019824.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005930190.1; XM_005930128.2.
DR STRING; 8153.ENSHBUP00000019824; -.
DR Ensembl; ENSHBUT00000029287.1; ENSHBUP00000019824.1; ENSHBUG00000022124.1.
DR GeneID; 102288892; -.
DR GeneTree; ENSGT00390000003140; -.
DR OrthoDB; 4157619at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001764; P:neuron migration; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR040685; Annexin-like.
DR InterPro; IPR045574; ASTN1_2_Fn3.
DR InterPro; IPR045575; ASTN_1_2_N.
DR InterPro; IPR040510; ASTN_2_hairpin.
DR InterPro; IPR026995; Astrotactin.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR16592; -; 1.
DR PANTHER; PTHR16592:SF2; ASTROTACTIN-2; 1.
DR Pfam; PF18411; Annexin_2; 1.
DR Pfam; PF19743; ASTN1_2_fn3; 1.
DR Pfam; PF19441; ASTN_1_2_N; 1.
DR Pfam; PF18577; ASTN_2_hairpin; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1362
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018582259"
FT TRANSMEM 194..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 855..1058
FT /note="MACPF"
FT /evidence="ECO:0000259|SMART:SM00457"
FT REGION 27..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1362 AA; 151203 MW; 46B0E6C637A5856E CRC64;
MARILVLHLR VLLVGLLLTG SLTVQANRGA TSPDEERDRE SDTETPCEVK TVTVSTLPVL
RENEFSFTGG ASGNVVGGGG AAEAGGVGGG GTGGGTGGGG AGGGGESRLL LFVRTDLPGR
ISVMDDLDNT ALPYFTLEMS GTGEEISQVH WKQQWLENGT LYFHVSMTES ELLAQTTQPT
AREPAHVLHE HMHLLHISVM GGLIALLLLI LLFTLVLYTR HRWCKRRRIP QKSASTEATH
EIHYIPSVLL GPQGRDSYRG SRSTHQHGSS VIGMPIRETP ILDDYDCDDE VDAGGHSLNS
TPNQIHNKLS DGKVLDDYGV GIQGHPDMMC KEDDIKHNFD KRAIDPNTES VEDLMQRFQD
SFRVPNTPTD MSHYQHVMHS SSTGRRRVLS HTREAGGVFG PQGESGSEPE DDNQMKFYTE
QHRGRRRSKG HPHSPLNKVT LTLITISTCV IAIVYATQDS CPLTVKVTLH VPEHFVADGS
SFVVSMGSFL DVSNWLNPAK LTLYYQTNSS TQWVQDYCGQ RTTEPCEQIC DQDTGECSCH
EGYSPDPVHK HLCVRSDWSR NEGPWPYANL EKGYDLVTGE QAPERIFRSF YSLGQGLWLP
VSKSFVVPPV ELSINPIASC KTDVLVTEDP GEIREEAMMS TYFENVEDLL ASFGPARDCS
KDNGGCKKNF KCVSDRQLDS SGCMCPEGLR PMKDGSGCYD YSRGIDCTDG FNGGCEQLCL
QQLVPLEDDP SSSNVLMFCG CVQEYKLAGD GRSCLLQSDN CDGPKCPKQD VYFNDTLFGE
MLHGYNNKTQ QVNLGQIFQM TFRDNNFIKD FPQLADGLMV IPLPVEEQCR GVLSEPLPNL
QLLTGDAQFS EAVGYPMVQQ WRVRSNLYKV KLSSITLATG FSKVLKTLST ESTRDELLAF
LQQYGSHYVS EALYGSELSC SIYFPSKKAQ QQLWLQYQKE ATEQGIGGGG RRELKSLPFI
SYLSALQKSQ LLSDDMVNGV EIRCEEKGSC PAGCHLCHHQ AMMGGVSGRG RTGNSRTGEQ
PSPIPVLLEV SRVVPLYSLV QDNVTKEALK SATMSSYWCA GKGDVIDNWC RCDLSAFSKD
GLPNCSPLRQ PILRLSPYLE PSSTMVALEW MDVEPLIGCK VSDYIIQHKR VEDPSEAEIY
TGEVLSLMDD LFSGLGSSCV VAGRRSGDHP HSVLYSVVFK CLEPDSLYKF TLYAVDSRGS
YSESSFVSVR TSCPVVDDTR AEETADKVYN LYNGYTSGKE QQMAYNLLME IPPPLLYRVQ
HHYNSHYEKF GDFVWRSEDE LGPRKANLIL RRVEKISLYC RSLLRSTHIQ SRTDTMAYVY
CRSEEARPPT NMWHGSLHDS RTACMEKLIS VQRNTYSSTK LR
//
