ID   A0A3Q2WPG2_HAPBU        Unreviewed;       815 AA.
AC   A0A3Q2WPG2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Metastasis suppressor protein 1-like {ECO:0000313|Ensembl:ENSHBUP00000027906.1};
GN   Name=MTSS1 {ECO:0000313|Ensembl:ENSHBUP00000027906.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000027906.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000027906.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_005935037.1; XM_005934975.2.
DR   AlphaFoldDB; A0A3Q2WPG2; -.
DR   STRING; 8153.ENSHBUP00000027906; -.
DR   Ensembl; ENSHBUT00000031460.1; ENSHBUP00000027906.1; ENSHBUG00000011382.1.
DR   GeneID; 102312853; -.
DR   GeneTree; ENSGT00950000183156; -.
DR   OMA; SSSHDQC; -.
DR   OrthoDB; 3875239at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   CDD; cd07643; I-BAR_IMD_MIM; 1.
DR   CDD; cd22060; WH2_MTSS1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   InterPro; IPR003124; WH2_dom.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS51082; WH2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          1..254
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   DOMAIN          787..804
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   REGION          259..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          450..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          529..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..316
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..366
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        468..504
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..568
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        577..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        672..693
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        748..774
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   815 AA;  88113 MW;  30C9532089B04AE8 CRC64;
     MEAVIEKECS ALGGLFQTVI ADMKSSYPIW EDFITKAGKL QSQLRATVVA VAAFLDAFQK
     VADLATNSRG GTRDIGSALT RMCMRHRSIE AKLKQFSTGF LEGLINPLQE QMEEWKRGVN
     TLDKDHAKEY KRARQEIKKK SSDTLKLQKK AKKADNFGRG DIQPQLDSAM QDVSDKYILL
     EETEKQALRK ALIEERQRFC CFVAMLRPIV DEEISMLGEV THLQTISEDL KALTSDPHKL
     PPASEQVILD LKGSDYGWSY QTPPSSPSTT MSRKSSMCSS TLPQQTPARL PSISSHDSGF
     ISSSQDQYTL SKSSSPLPAE KKACPTSSPS EMSETGLLHS DCSTPSSLAD TTAPQPSTDK
     LSNGFDHYSP ASSPYLHSNG GSLGSVSNTA FPFFPPSSST STSCPTRSWS RPASALLPDY
     PPYCTLGSPM MPSSRVPSWK DWAKPGPYDQ PMVNTLRRKK DKESPAVVDS NGSMNCDNSP
     PSAQTAAPAA LQTPSQSALV QDKNRNTPAA VRAGDIEAQD DLALALSRGL ELDTQRSSRD
     SIQCSSGYST QTNTPCCSED TIPSQVSDYD YFSMAGDPES EQQQSDFDKS STIPRNSDIT
     QSYRRMFQAK RPASTAGLPS SQVPYPGPGA YHTGPYPPTP IHTGAYASTP TAQYPPTPTG
     HGPVIVTPGV ATIRRTPSSK PSGRRSGSVT GTGPIPIRTP VVPVKIPTVP DMPGAVNGNR
     GEEMVGREES PSSPTFTGEV DPGTLPMASW SGQATTNPPN LPNYVSQQHL QSEMRQEGGG
     DDSGEQEEGD MLMAIRKGVK LKRTFTNDRS APRIA
//