ID   A0A3Q2WRU1_HAPBU        Unreviewed;       459 AA.
AC   A0A3Q2WRU1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Forkhead box J1 {ECO:0000313|Ensembl:ENSHBUP00000029413.1};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000029413.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000029413.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
CC   -!- SIMILARITY: Belongs to the FOXJ1 family.
CC       {ECO:0000256|ARBA:ARBA00034770}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_005948045.1; XM_005947983.2.
DR   AlphaFoldDB; A0A3Q2WRU1; -.
DR   STRING; 8153.ENSHBUP00000029413; -.
DR   Ensembl; ENSHBUT00000019492.1; ENSHBUP00000029413.1; ENSHBUG00000013840.1.
DR   GeneID; 102299977; -.
DR   CTD; 767737; -.
DR   GeneTree; ENSGT00940000156895; -.
DR   OrthoDB; 5385885at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:GOC.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0090660; P:cerebrospinal fluid circulation; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0003146; P:heart jogging; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   CDD; cd20023; FH_FOXJ1; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR047512; FH_FOXJ1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR047513; FOXJ1.
DR   InterPro; IPR018122; TF_fork_head_CS_1.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46805; FORKHEAD BOX PROTEIN J1; 1.
DR   PANTHER; PTHR46805:SF1; FORKHEAD BOX PROTEIN J1; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00657; FORK_HEAD_1; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   3: Inferred from homology;
KW   Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          140..234
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        140..234
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          304..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  50293 MW;  402D4B4DAF197D59 CRC64;
     MLSLSCADPW AEGSVGLEEE VVTAAAQAEE RDGVSGTDSS SCSVSLDDSL TSLQWLQEFS
     ILGTNVPHHT HHQHHLFGHQ QLGSDAPASP LAGDPASIGM PLTPGKPTAA AYSRMQPLPG
     IVAHGHCPDD VDYKTNAHIK PPYSYATLIC MAMQASKKSK ITLSCIYKWI TDNFCYYRHA
     DPTWQNSIRH NLSLNKCFIK VPRQKDEPGK GGFWKIDPQY AERLLSGAYK KRRMPPVQIN
     PALRNRLGVN MQPQPRGQIG LCVNPESQRL LREFEEATGA DQNWDPHLAE GTMLGSWPVV
     RGRSGLKRKQ GSRNGAAKAP RRSSSPLLSM DEQKEIGPLK GDFDWDALLD SALSGELTLE
     GGEPLSPIMK EEDLTVRGTH ISPVEAPAGS AEAERSNNMS DFDEETFLAT AFLENPWPEE
     EADHGRSDFL CSSTVNLDQL FGLEDPLGGD PSSRMDTLL
//