ID   A0A3Q2WSI0_HAPBU        Unreviewed;       481 AA.
AC   A0A3Q2WSI0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000029713.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000029713.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A3Q2WSI0; -.
DR   Ensembl; ENSHBUT00000020061.1; ENSHBUP00000029713.1; ENSHBUG00000014311.1.
DR   GeneTree; ENSGT00940000158727; -.
DR   OMA; SPFLILX; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796:SF60; PATCHED DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..35
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           36..481
FT                   /note="SSD domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018721909"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        310..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        338..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          309..439
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   481 AA;  54082 MW;  30AA526924C00BF8 CRC64;
     RPAHLDSATM PGSKPVKRSF FLILMLAYLD TLYKCAVTTD PCHCPATLRM DSRRTDCLTK
     PLSRLFENLG SKVGSYPLYF FIVPVLLSAA LSGGFIFLEG RQDNSLERQF TPTKGPSKAT
     RAFVKENFPY NYSMFSEDRQ YDKGSFASLI AMARNSRNLL DTLVLEDIIS LNNKILDITV
     DNGRLGFNEL CARANGECVS NIILEILSYS LTNQTSITYP VHMHKATPLF LGAVLGGVIT
     DDSDSVRNAE AVKLFYYLDD RESTAEASKL WLREFKKLLS DNTDSEHIYV SYYTSKSKQD
     EIDSHTTDGF PLFLIAYACA VTFSVISCLR LDNVRNKVWV AVFGILSAVL AVLSGFGLLL
     YIGVPFVITV ANAVFLLLGI GLNNMFIMVS DWRHTHVNDP VPKRMAHTYK EAIMPITITA
     VTDVLKFFIG VKSYFPSMQF NSRIFLLLPS APLCHRNKDR NTAENIKCFS FNLHNQNVYF
     F
//