ID A0A3Q2WTW2_HAPBU Unreviewed; 899 AA.
AC A0A3Q2WTW2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Polyhomeotic homolog 3 {ECO:0000313|Ensembl:ENSHBUP00000029280.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000029280.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000029280.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_005936701.1; XM_005936639.2.
DR AlphaFoldDB; A0A3Q2WTW2; -.
DR STRING; 8153.ENSHBUP00000029280; -.
DR Ensembl; ENSHBUT00000019326.1; ENSHBUP00000029280.1; ENSHBUG00000013595.1.
DR GeneID; 102290134; -.
DR CTD; 80012; -.
DR GeneTree; ENSGT00940000162952; -.
DR OMA; DRHAVQX; -.
DR OrthoDB; 4251858at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF88; POLYHOMEOTIC-LIKE PROTEIN 3; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 683..717
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 835..899
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..427
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..598
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 95616 MW; 86D6C26542DA7756 CRC64;
MDRRSPGDRQ ADTSKTVTTA SSSSVVTMAT PSSSAQPPST SLSIIPPDRQ AVQVIQHAMN
RPQSMAAQYL HQMYAAQQQH FMLQTAALQQ HQHPAHLQSL AAIQQASVCQ RSPSSSTGSL
VQAAGVSQNS ITLPASPVTA RLIGRTQTST ASAATISQQA MLLGNRPASC NQAQMYLRTQ
MLILTPAATV AAIQSDLPTV TSCSSLPTSS QNLALRTHLP GALATAHSVI LKPSTESQAL
PAATSLSKNP VCGLKSTQLT DGSTETAPSD ATSLVSGPQI ITPAYPPVQT HTLVKQQLSC
PVGQQVAHHQ LIVQQATGGA PSSRQLQPIA LRVAPRDTHS NPLPLSVKRL TASSTHSQLR
NEPPALSSSS SPLVTSMLAS SPQTSVPAAA VQPQPPPLVA APQRRTSFPQ SQQPPPPPPP
LILPRLPQNP PASLHRVSLH SVRALAVHSG QVLLTERELP VAEALVQMPY QNLPPPQTVA
VDLKVHPVKH NETAPLGQKC NVNSLSSEER KDPPSSEQDG TATPPNQNGS AVTGSSFITP
SHWRSPPVEE SSQLTTTDNS GSSGTNNPPP PPPSPLPPPL LPASAKVPSQ PPSAPASLPG
SPKRSTHVLT HLVEGFVIKE GLEPFPVGRS SLLSEQQASL PEPQDVPTNG DAADDSPLDA
DQSDSSDSEM ENDGPTGEVA ELGESVPDVL QCEYCGSSGY ACTFLRSKRF CSMSCVRRFS
VSCTKRIAVL HAGRLAHRPL GRRGRPPSRV NGASREHFVM QAHRSFGSKE TQQSSPREED
EHHEEEEEEE EPPVPMTTRL RKQAERAQER VREQRTVETI IVSDAEEDVG CPSQWNVEQV
SSYISTLPGG ADVAEEFRSQ EIDGQALLLL TEDHLVSTMN LKLGPALKLC AHINSLKDA
//
