ID A0A3Q2WW65_HAPBU Unreviewed; 740 AA.
AC A0A3Q2WW65;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Collectin-12 {ECO:0000256|ARBA:ARBA00017460};
GN Name=COLEC12 {ECO:0000313|Ensembl:ENSHBUP00000031219.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000031219.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000031219.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005922552.1; XM_005922490.2.
DR AlphaFoldDB; A0A3Q2WW65; -.
DR STRING; 8153.ENSHBUP00000031219; -.
DR Ensembl; ENSHBUT00000023006.1; ENSHBUP00000031219.1; ENSHBUG00000016761.1.
DR GeneID; 102298500; -.
DR GeneTree; ENSGT00950000183074; -.
DR OMA; LIHEALW; -.
DR OrthoDB; 4613106at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03590; CLECT_DC-SIGN_like; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR033989; CD209-like_CTLD.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN ALPHA-1(X) CHAIN; 1.
DR Pfam; PF01391; Collagen; 2.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 612..729
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 434..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 104..138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 177..243
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 544..580
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 80634 MW; 6C52CB90081711F8 CRC64;
MKDDFADEEE VQSFGYKRFG IQEGTQCTKC KNEWALKTSI ALLYVLCTLL TIAVAILGYK
VVQRVDSVSE GIANYGGKII AVETDLKKLD DQTGEKSENT TTEIQAFKNN IWTLQRQLSA
VEERIRSDQV KLNQLQNIGS DIQSSQGSIQ GLLNINTATL RSVNGSLQSY GSIIGGLQED
TARLQRELQQ QVKLQNQALL SISSLNLTQD QQRGLIAALQ RSVDDTSQAI HKMRNDFQSL
EQNTRQTRSD TEWLRSKVEN LQILASNTSA LAKSNNDSLE DVGTQLTFIA NQLQNTSSLA
EVHDQTLREI MDQQRDFGNL TSTKFDRLEV RLDESEQSID RVTGNISFTT QLLGAINLNL
NDLRTCSETV GRHSDFLLHL NNSMADVRTD ATSLRSQQEE LAARMDKEVT SLSIVMEEMK
LVDTKHSQLI TNFTILKGPP GPRGPRGDKG PQGLPGQSGQ KGEKGDKGAP GIRGPRGEQG
SPGPPGLPGL KGLPGIPGSP GSKGPRGSGG RAGPPGTKGE PGSAGLPGRD GQPGPQGVQG
PPGIRGPIGP PGEQGPRGLP GPVGPSGPVG PPGQPGLPIR VPAVPFGPVS LQDEAVGPTI
WAPGCPAEWL NYKDKCYFFS KDLQSFDHAK TTCESMSGSL LIINDMEEQK WLKRQIFGKG
YFWMGLTDRE KERTWRWLDG TEPTFTKWKP GQPDNWGHGH EEGEDCAGLT HEALWNDFSC
EDLISYICEK EMETSRSPGS
//
