ID A0A3Q2WX39_HAPBU Unreviewed; 484 AA.
AC A0A3Q2WX39;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000031594.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000031594.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR AlphaFoldDB; A0A3Q2WX39; -.
DR STRING; 8153.ENSHBUP00000031594; -.
DR Ensembl; ENSHBUT00000023727.1; ENSHBUP00000031594.1; ENSHBUG00000017375.1.
DR GeneTree; ENSGT00940000156269; -.
DR OMA; NINFYVS; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF104; T-BOX TRANSCRIPTION FACTOR TBX1; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 58..245
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 406..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 54752 MW; E5C7D9569CC4F71A CRC64;
VHALWLHCVH TRVGRCDIVN MPESTPWSSA LPATTFGNTD MEKDFPAVLT FKGVSVVLEN
SNVWKQFYKC GTEMILTKQG RRMFPYCRYR LTGLDPNQQY SLVLSIVPSG QYRYRWSASR
WEVTGRAEHQ NQGLIRAFSH HYSPCRGSDW MNSLVSFYKL KLTNNSQDQD GHIILHSMHR
YIPRLHIIPV PDGGMPTADK PVVMGHESMT FTFPQTEFMA VTTYQNFRIT QLKINHNPFA
KGFREDGNNP RLNRIAREAQ AIVKTEYQPT VIEPAEPSEN QEEVLDLRWL IKMPLPHAVP
PQMKGFCTEI MIKSTCLVSI TNINFYVSYS ANSQNDSASL SNVQETRLVL KPIMSKPARK
DEPYVPCIRG KHALGDLVLV APKQESAATS VAPEVQQDLK VWMSPKARSV TANSSTSTPG
SSPRFCKRRK KMNRRWSNSR GRECKTAAAS STVVHSPSLT GAMQPEMDDI EGLLFVSFTS
KVKH
//
