ID A0A3Q2X126_HAPBU Unreviewed; 344 AA.
AC A0A3Q2X126;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Major histocompatibility complex class I-related gene protein-like {ECO:0000313|Ensembl:ENSHBUP00000033169.1};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000033169.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000033169.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
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DR RefSeq; XP_014192735.1; XM_014337249.1.
DR AlphaFoldDB; A0A3Q2X126; -.
DR STRING; 8153.ENSHBUP00000033169; -.
DR Ensembl; ENSHBUT00000026733.1; ENSHBUP00000033169.1; ENSHBUG00000019909.1.
DR GeneID; 102289525; -.
DR GeneTree; ENSGT01100000263475; -.
DR OMA; EVVGYNQ; -.
DR OrthoDB; 3840485at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF237; MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..344
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018746745"
FT TRANSMEM 310..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 201..288
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 344 AA; 39372 MW; ED3E7E01D21774B3 CRC64;
MNSLCLFLLS CHVSSAVKHS LKYFITASSG ISDFPEFVGA ALVDGVLVGY CDSSLRRAEP
KLDWMQELIK KDPQHLEWYT QKCSGNQQVF RANINSLKKR LNQTAGVHIF QRMNGCEWDD
ETDKITGFNQ YGYDGEDFIA LDLQTLTWIA PKPQAVVTKL QWDTEKPRLE HNKNYYINRC
PDWLKKYVKY GRSFLQRTVL PSVSLLQRTP SSLVSCHATG FYPERAMMFW RRGEEEIHEG
VEHGEILPNH DGSFQMSVEL NVSSIKPEDW RRYDCVFQLS DVKEDIITKL DKTAIRTNWV
SPSVFPVGPV VGGVGGVLLL LAVFGFFIWR RNNNGFELTN TGEQ
//
