ID A0A3Q2ZE89_KRYMA Unreviewed; 625 AA.
AC A0A3Q2ZE89;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=BED-type domain-containing protein {ECO:0000259|PROSITE:PS50808};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000000940.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000000940.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q2ZE89; -.
DR Ensembl; ENSKMAT00000000971.1; ENSKMAP00000000940.1; ENSKMAG00000000737.1.
DR GeneTree; ENSGT00940000158431; -.
DR OMA; WWHEREE; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 1.10.10.1070; Zinc finger, BED domain-containing; 1.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR003656; Znf_BED.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR46169; DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A; 1.
DR PANTHER; PTHR46169:SF15; DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A; 1.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF02892; zf-BED; 1.
DR SMART; SM00614; ZnF_BED; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF140996; Hermes dimerisation domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50808; ZF_BED; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00027}.
FT DOMAIN 12..70
FT /note="BED-type"
FT /evidence="ECO:0000259|PROSITE:PS50808"
FT REGION 446..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..465
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 69573 MW; 23856FCE9876CD58 CRC64;
MASSCRKLTP STFKSDVWAH FAFLSKSGTQ EVDKSKVVCK LCQRELKYCS NTTNLRNHLT
RYHADALQKA QPVDSKQTQI DKSFISKLPS SSARAQKITK SVAVFICKDL RPYSVVENKG
FKNMLKILEP RYAIPTRKYM TEVAVPSLYT EVKTDVLESL KSAERVALTC DGWTSRATDP
YVTITSHFIS DEWELVSNVL QTRPLHGSHT GSNIANLLTE AINEWGITGK VPAVVTDNAA
NMLAAVGLTD LLHVGCFAHV LNLASQAALK TPAVTRLLGR VRRISAFFHR STLACHALKK
NQKLLDLPQH KLLTDVSTRW NSALDMLERF LEQQPAVSAA LLAPEVRKQE KDLCSLTEAD
ITAAEDIAQA LKSLKKATLV MSQESTPSLS VIAPLKERLL EDMQPSSSIN IYITFLYLGL
KDELSIAAAL DPRFKALLFL SDDDEREEQQ SGLMDEDREA IEQQGEPVDD PSGPSPKKAR
DSCALADLFG SAYTTPVAVS RTTDTKALDE VVRYKEVQPL PLSTNPLNWW REHEGEYPLL
SCQAKRYLCI PGSSVPAERI FSTAGDIVTA QRSALKPEHV DQLLFLNKNL HRGIGNEGSR
QEGVKENHRK KSDDTMYKHR LRKAD
//
