ID A0A3Q2ZLX2_KRYMA Unreviewed; 536 AA.
AC A0A3Q2ZLX2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger SWIM-type containing 2 {ECO:0000313|Ensembl:ENSKMAP00000004753.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000004753.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000004753.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q2ZLX2; -.
DR STRING; 37003.ENSKMAP00000004753; -.
DR Ensembl; ENSKMAT00000004839.1; ENSKMAP00000004753.1; ENSKMAG00000003610.1.
DR GeneTree; ENSGT00390000006826; -.
DR OMA; RNQKWRS; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16494; RING-CH-C4HC3_ZSWM2; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR007527; Znf_SWIM.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR039903; Zswim2.
DR PANTHER; PTHR21540:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2; 1.
DR PANTHER; PTHR21540; RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF04434; SWIM; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS50089; ZF_RING_2; 2.
DR PROSITE; PS50966; ZF_SWIM; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT TRANSMEM 501..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..82
FT /note="SWIM-type"
FT /evidence="ECO:0000259|PROSITE:PS50966"
FT DOMAIN 148..200
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 231..282
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 334..374
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 433..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 60529 MW; 27D0DDDF758806B4 CRC64;
MLRRTGCRNT ASDAVRSHQD QALDTTMFLI RSCGPAAFLL RENGEARDLK VCLGDPHTCS
CSVFSREREP CKHICWVLLR KFRLPREHEY SFQPGLVERQ LLELLQGLHR AHRTELDASA
ASGTLGRAVP GPEAGSVCRK VIQAQDVCPI CQEELLQKKQ PVSYCRFGCG NSVHISCMKV
WADHQTPSDQ QEMVRCPLCR EDFCSVKLLQ EQVKNAAKLF TAAERERANK HLGAVCHSCR
VCPVSGTCFR CAVCSRFYLC EECVQKGCHS QHPLASRAVS RSDRAQRPIR IRSFLNPPPL
LRAVAELSPS RVLERLPAVR VRPGSQLLNE GLQCRICLQG FSVGQTVRTL PCHHKFHVDC
VDQTLLETNS CPLDGFIIYG PLTWRTTQRK TCPTMASSKQ QENNVQDLFV PGVALQVLPP
RGALNFEVPT SMPQKDATAA GGERQTRAPF TAESGRPLNH DICSRSSKQR AANMPIRTPQ
ISFLITADWK QVICIPSRKS LILFNIFWTF FMFSIFTKYI FYLKDNFMHW LVSWRL
//
