ID A0A3Q2ZN44_KRYMA Unreviewed; 623 AA.
AC A0A3Q2ZN44;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Potassium voltage-gated channel subfamily D member 2-like {ECO:0000313|Ensembl:ENSKMAP00000004425.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000004425.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000004425.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_017261409.1; XM_017405920.1.
DR AlphaFoldDB; A0A3Q2ZN44; -.
DR STRING; 37003.ENSKMAP00000004425; -.
DR Ensembl; ENSKMAT00000004510.1; ENSKMAP00000004425.1; ENSKMAG00000003369.1.
DR GeneID; 108230062; -.
DR KEGG; kmr:108230062; -.
DR CTD; 3751; -.
DR GeneTree; ENSGT00940000155472; -.
DR OMA; KDFFFHE; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003975; K_chnl_volt-dep_Kv4.
DR InterPro; IPR024587; K_chnl_volt-dep_Kv4_C.
DR InterPro; IPR021645; Shal-type_N.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF265; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF11879; DUF3399; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11601; Shal-type; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01497; SHALCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..623
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018523740"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..139
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 515..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 69916 MW; 072170C409541CDF CRC64;
MAAGVAAWLP FARAAAIGWM PVASTPMPIP PQDKRKAQDG LIVLNVSGTK FQTWRTTLER
YPDTLLGSTE RDFFFHEETN EYFFDRDPDI FRHILNFYRT GKLHYPRQEC ISAYDEELAF
FGIIPEIIGD CCYEEYKDRR RENAERLQDD EEMDMNNDVT PVNLTFREYL WRAFENPHTS
TLALVFYYVT GFFIAISVMA NVVETVPCGT LPNRSKEVSC GDRYALAFFC LDTACVMIFT
VEYLLRLIAA PSRCKFMKSV MSVIDVVAIM PYYIGLVMTD NDQVSGAFVT LRVFRVFRIF
KFSRHSAGLR ILGYTLKSCA SELGFLLFSL TMAIIIFATV MFYAEKGSSA TKFTSIPAAF
WYTIVTMTTL GYGDMVPKTI VGKVFGSICS LSGVLVIALP VPVIVSNFSR IYHQSQRAEK
RRAQRKTRLA RIRAAKIRGT NAYMRYKQNG LLIDSLEEAS KQAGQALVGK AATPPFESQH
HHLLHCLEKT TNHEFVDEQT FQANCMEVSV VNKSGSRSSS LSSSPHGLGS CCSRRHKKKS
SFSPPSTNNQ ELSTIQIRER PVSNSRSSLN AKLDETVPLK CDEPYITPSM VSLSAPVVTS
ADEDASTTTT AYSQSNIVRV SAL
//
