ID   A0A3Q2ZP83_KRYMA        Unreviewed;       654 AA.
AC   A0A3Q2ZP83;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=MutS homolog 5 {ECO:0000313|Ensembl:ENSKMAP00000005603.1};
GN   Name=MSH5 {ECO:0000313|Ensembl:ENSKMAP00000005603.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000005603.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000005603.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q2ZP83; -.
DR   STRING; 37003.ENSKMAP00000005603; -.
DR   Ensembl; ENSKMAT00000005702.1; ENSKMAP00000005603.1; ENSKMAG00000004097.1.
DR   GeneTree; ENSGT00550000074977; -.
DR   OMA; METHQDG; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 1.10.1420.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          490..506
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|PROSITE:PS00486"
SQ   SEQUENCE   654 AA;  73365 MW;  4D9C57F73E2A4186 CRC64;
     MADTSDNHDL QLLDRSNPQY KPEVVTYPNA DFLEVGKQRL LSAHLPFLPG SISDRDKMSY
     LTSCITFDSP LMLRAVGALL KCLDRRRVGV ELEDSSVGVP ILQFHAYTKG VVYIDRDTYV
     LQIFKSDLHP SVYKLQSGEK EGLSLYILNR CKSKSGSKLL QWFLRPTQEL TVLRRRQEVI
     RFFTSPRHSD ILKTLQASLR NIRNIPMSLS NTKVTDWQSL YKTVYSAVCI RDTARNLPRS
     VQLFRDIGES FSDDLHHIAN LISRVVDFEA SLEENRFTVK PNVDPAIDEE KRKMMGLSDF
     LTDVARKELE NLDPRISSCC VIYIPLIGFL LSVPRLPSMV EKEDFEMEGL EFMFLSEDRL
     HYRSQRTREL DNLLGDLHCD IRGLLFHPLL ELCSPVYVAN NFQSSESEGR VKIITGPNSS
     GKSIYLKQVG LIAFMALIGS DVPAKEAEIG LLDGIFTRMQ SRESVSVGLS TFRIDLNQMA
     LALNSSTGNS LVLIDEFGKG TNTVDGLSLL ASSISHWLSK PPADVPHILL ATNFHSLLQL
     GLLPASELLS FLTLETAVDG DELVFLYQLK EGICQSSYAA NIAALAGLPT CLVHRAVEAS
     EHYRTGKPIK HIDKASSEEQ AKSVVQRFLS LDLEDKELEL QSFMKDELLP SAGE
//