ID A0A3Q2ZX25_KRYMA Unreviewed; 411 AA.
AC A0A3Q2ZX25;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DMRT like family A1 {ECO:0000313|Ensembl:ENSKMAP00000008438.1};
GN Name=DMRTA1 {ECO:0000313|Ensembl:ENSKMAP00000008438.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000008438.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000008438.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
CC -!- SIMILARITY: Belongs to the DMRT family.
CC {ECO:0000256|ARBA:ARBA00006834}.
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DR RefSeq; XP_017269893.1; XM_017414404.1.
DR AlphaFoldDB; A0A3Q2ZX25; -.
DR STRING; 37003.ENSKMAP00000008438; -.
DR Ensembl; ENSKMAT00000008566.1; ENSKMAP00000008438.1; ENSKMAG00000006350.1.
DR GeneID; 108234859; -.
DR KEGG; kmr:108234859; -.
DR GeneTree; ENSGT00940000160640; -.
DR OMA; CGSRDQS; -.
DR OrthoDB; 5401440at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.1040.10; DM DNA-binding domain; 1.
DR InterPro; IPR001275; DM_DNA-bd.
DR InterPro; IPR036407; DM_DNA-bd_sf.
DR InterPro; IPR005173; DMA.
DR InterPro; IPR026607; DMRT.
DR InterPro; IPR046472; DMRT5_1_DMB_dom.
DR PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR PANTHER; PTHR12322:SF71; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1; 1.
DR Pfam; PF00751; DM; 1.
DR Pfam; PF03474; DMA; 1.
DR Pfam; PF20624; DMRT5_DMB; 1.
DR SMART; SM00301; DM; 1.
DR SUPFAM; SSF82927; Cysteine-rich DNA binding domain, (DM domain); 1.
DR PROSITE; PS40000; DM_1; 1.
DR PROSITE; PS50809; DM_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00070}; Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00070}.
FT DOMAIN 52..99
FT /note="DM"
FT /evidence="ECO:0000259|PROSITE:PS50809"
FT DNA_BIND 52..99
FT /note="DM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00070"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 43707 MW; EC2D253A54886513 CRC64;
MESRIRPLAM AAHPSSPLGG LPMSPSLLRH PPLFLRACSP ALERGYPRTP KCARCRNHGV
VSALKGHKRF CSWRDCVCAK CTLIAERQRV MAAQVALRRQ QAQEESEARE LRLLFPGSGV
GARPGMAQGA PLGRGGAAVT APAAPCFDVF GAQSHKEDDK VSKFSFYNGF MGQPLFVSPR
VPSPSDKKET SPSRDTTASV PSEDRSPSPP CDRLSDHAQS PQTSLSSSDP ESGSELEKPK
DCPSPSLDRD PASLMAKIFP HQQRDTLESM VRTCRGDIVK SIELVLSSKE NKMDPGGVSP
SGLLRPPAAL PGALGALGAA KSAFSPLHGP PAPGGDGLYG LGPRLGVSPL RLAPGSGDFM
APYMTSGLMP LLTLRPPLDS FPGMIRDFSY IQSKDSLCSA AGLYTRLNSD K
//
