ID A0A3Q3A051_KRYMA Unreviewed; 754 AA.
AC A0A3Q3A051;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Rap1 GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSKMAP00000009616.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000009616.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000009616.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017264994.1; XM_017409505.1.
DR AlphaFoldDB; A0A3Q3A051; -.
DR Ensembl; ENSKMAT00000009762.1; ENSKMAP00000009616.1; ENSKMAG00000007163.1.
DR GeneID; 108232028; -.
DR GeneTree; ENSGT00940000156138; -.
DR OrthoDB; 25782at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF68; ZGC:175180 PROTEIN; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT DOMAIN 232..448
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 28..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 735..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 84013 MW; 1A63988E1CF6DC18 CRC64;
MPQRKRSFTF GAYGGVDKTF SKARGIWKQD GSDPRISAPL EPPLLQPTLT HTASPLHKGS
RMDEQRCSFP PPLKTEEDYI PYPSVHEVLG RKSPFPLILL PQFGGYWIEG TNHELSEAEL
PRPPSPNTRT KLECNTTATL FRKHFLGKEH FNYYSVDSNL GHLVFSIKYD VIGDQEHLRL
MLRTKLKTHQ DVIPISCLTE FPNVFQMAKL VCEEVNVDRF YPVLYPKASR LIVTFDEHVI
SNNFKFGVIY QRFGQTSEEE LFGNSEESPA FVEFLEFLGE KIELHNFKGF RGGLDVTHGQ
TGTESVYCNY RNKEVMFHVS TKLPYTEGDT QQLQRKRHIG NDIVAIVFQD ENTPFVPDMI
ASNFLHAYIV VQVVNPCSEN ILYKVSVTAR DDVPFFGPAL PDPAVFKKGP EFHEFLFTKL
INAEYACYKA EKFAKLEERT RSALLETLYE ELHMNSQAIM GIGGEEDKIE NGSAGGGGFF
ESFKRVIRSR SQSMDAVSLT FKKPYTISST VSSTFNHSTT ESPKFPGISL LVPGKSPSKY
GRRGSAIGIG TVEESLIIPG KSPTRKKSGP FSSRRSSAIG IENIQEVQEK SSRDPSPNTQ
KTPDSGHVSQ DPKSDNSDQS SPEVLTTAKN SSYLCGRTPS IPEAHDLSRS SSNASSFASV
VEENEAEAAE DYDTGMESLS SAGTPHKRDS LTYSTWLEDS VSCTSSNSRG SSPGPGKPDR
GKISDVRIKL ERSHDNQSTQ PQSHTPSGRR ETCI
//
