ID   A0A3Q3A1D8_KRYMA        Unreviewed;       827 AA.
AC   A0A3Q3A1D8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Rho GTPase activating protein 17 {ECO:0000313|Ensembl:ENSKMAP00000009590.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000009590.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000009590.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017273972.1; XM_017418483.1.
DR   AlphaFoldDB; A0A3Q3A1D8; -.
DR   Ensembl; ENSKMAT00000009737.1; ENSKMAP00000009590.1; ENSKMAG00000007197.1.
DR   GeneID; 108237208; -.
DR   CTD; 550254; -.
DR   GeneTree; ENSGT00940000156201; -.
DR   OMA; CIDSIYI; -.
DR   OrthoDB; 7959at2759; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04386; RhoGAP_nadrin; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR   PANTHER; PTHR14130:SF3; RHO GTPASE-ACTIVATING PROTEIN 17; 1.
DR   Pfam; PF03114; BAR; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00721; BAR; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51021; BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          14..260
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   DOMAIN          266..456
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          491..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          599..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          180..207
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        505..522
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..733
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        734..751
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        752..772
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        781..810
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        811..827
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   827 AA;  89374 MW;  88ED1CF67D73D596 CRC64;
     MKKQFNRMKQ LANQTVGRAE KTEVLSDDLL QIERRMELVR VVSHNTHKKM VSCLQGHIGA
     DAEKRHSVPR LYTGNGQKKL PLTALSQAMV EGGNQLGEDS LIGKMMEVCG EAENRLASEL
     MQHELQIEKD VLDPLSQLAE VEIPNILKQR KQLAKLVLDY DSARARWLQA TKSIISGTNT
     QALTAKADLL KEEVDEAMNK VELCKDQLAA DMYSFFSKEG DYAHYFVTLL EAQADYHRKS
     LTVLESVLPT IQAQQDSWME KPAFGTALDD HLKRSGREIA LPIEACVMML LETGMKEEGL
     FRIAAGASKL KKLKAALDCS TSQLEEFYSD PHAVAGALKS YLRELPEPLM TYQLYDEWIQ
     ASSVSDPDKR LQALWLVCDQ LPKNNKNNLR YLVKFLARLA QESEVNKMTP SNIAIVLGPN
     LLWAKTEGSL AEMAAATSVH VVSIVEPIIQ HADWFFPEDV EFNVSGMFVM PAPASNHNNH
     VDYDCSTIER KRPGSVVVPE NDATRKDNTS NKHSDHTLRR GSNTLGRKQH TSPAFQPPLP
     PVEAQGLGHG AGPSPQPPAE PQPQAPPGGS GFDSSQHSLA QSLAALAAAQ QLLAQHTEEL
     SNPKVRDCTP APTPVLQRNG TGGGGPVAPS GTGSMGPSPH MMRRGTKKQA PAPPKPSNPP
     PSQPCNSANH ASSSGSSQSL SPTARPPPSH SPTSPSSPTS QPSATPRRHS NNPPPIQAPN
     HPPPEPPSQA SPPAQPTSLS QAVGDQQSLE PSPPGTPTPP DTPPPPSATS QEVAAPPSPS
     PYQSGSLPRP RPVPKPRNRP TIPPPPQPNT TSSETNGICA SAYKTMG
//