ID A0A3Q3A5B9_CHICK Unreviewed; 398 AA.
AC A0A3Q3A5B9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Myocyte enhancer factor 2B {ECO:0000313|Ensembl:ENSGALP00010042334.1};
GN Name=MEF2B {ECO:0000313|Ensembl:ENSGALP00010042334.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010042334.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010042334.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010042334.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_430389.3; XM_430389.5.
DR AlphaFoldDB; A0A3Q3A5B9; -.
DR SMR; A0A3Q3A5B9; -.
DR STRING; 9031.ENSGALP00000065629; -.
DR PaxDb; 9031-ENSGALP00000023559; -.
DR Ensembl; ENSGALT00010068892.1; ENSGALP00010042334.1; ENSGALG00010028444.1.
DR GeneID; 426373; -.
DR CTD; 100271849; -.
DR VEuPathDB; HostDB:geneid_426373; -.
DR GeneTree; ENSGT00940000160699; -.
DR InParanoid; A0A3Q3A5B9; -.
DR OMA; PNAIASW; -.
DR OrthoDB; 448298at2759; -.
DR Reactome; R-GGA-525793; Myogenesis.
DR Proteomes; UP000000539; Chromosome 28.
DR Bgee; ENSGALG00000037558; Expressed in granulocyte and 7 other cell types or tissues.
DR ExpressionAtlas; A0A3Q3A5B9; baseline and differential.
DR GO; GO:0030054; C:cell junction; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005667; C:transcription regulator complex; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0042826; F:histone deacetylase binding; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0007507; P:heart development; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; Transcription factor, MADS-box; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR PANTHER; PTHR48019:SF109; MYOCYTE-SPECIFIC ENHANCER FACTOR 2A; 1.
DR PANTHER; PTHR48019; SERUM RESPONSE FACTOR HOMOLOG; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SRF-like; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
SQ SEQUENCE 398 AA; 42387 MW; B001D9672A5D0D6E CRC64;
MGRKKIQISR ILDQRNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNRLFQYAST
DMDKVLLKYT EYSEPHESRT NSDILETLKR KGLGLESHEL ELEEGLDPGE KLRQMNEGMD
LTVARPRFYS PVPLPEVPYG SSPSSSSDGA LGSASSSPQS QGRPPAFKPT APKPSGRSPG
PMPPGIGYPL FPAGSLNRAL ATKTPPPLYL GADGQRRSGG STARPLYSGL QTLNPVLASG
SASIPSHSLT GFPFLAPAQA AEFGAGEAPP PPGFLQPGPP APWQPPRDMA ALGASSRIVP
TEDLAPGSSP QPHAISIKSE RVSPGLGCPS GAPQPSQGSL TSLSEAPQGA ADLQPRDDYS
KGYPYPPPPP RPLAEEQRAT AAVPVPARRA QAEDAWQR
//
