ID A0A3Q3A700_KRYMA Unreviewed; 1335 AA.
AC A0A3Q3A700;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Partner and localizer of BRCA2 {ECO:0000313|Ensembl:ENSKMAP00000012218.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000012218.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000012218.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017280375.1; XM_017424886.1.
DR STRING; 37003.ENSKMAP00000012218; -.
DR Ensembl; ENSKMAT00000012402.1; ENSKMAP00000012218.1; ENSKMAG00000009182.1.
DR GeneID; 108240989; -.
DR KEGG; kmr:108240989; -.
DR CTD; 79728; -.
DR GeneTree; ENSGT00390000014423; -.
DR OMA; GHCQKED; -.
DR OrthoDB; 5404130at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR042417; PALB2.
DR InterPro; IPR031920; PALB2_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR14662; PARTNER AND LOCALIZER OF BRCA2; 1.
DR PANTHER; PTHR14662:SF2; PARTNER AND LOCALIZER OF BRCA2; 1.
DR Pfam; PF16756; PALB2_WD40; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT DOMAIN 1028..1331
FT /note="Partner and localiser of BRCA2 WD40"
FT /evidence="ECO:0000259|Pfam:PF16756"
FT REGION 55..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 14..48
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 64..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..457
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..901
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..927
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 144613 MW; 8BAE436E0F60B5FE CRC64;
MDINVQHSEE QLRNTLHCDD KEKLRRKLAQ LQREYLKTAQ RLQRAERLEA VQRHVRSRIS
QQKHQELEAT SSSSSSIQNA NNAVAQGLPP RQAHTEGPAD SDTSRRNQVI RFMLPPDAAC
PQTADPGNDA AVGYRASPTL RLRSRRSRLR LERRSAEAGN DADSNQQGQQ QEGKVESAKT
VVEEEGTVEA KGGDEANGSE ELFSATESPS LLLTHCNTQG HTETGDVLGK ENLRGQEQQA
KEADLTTEER GENGTQNEET NAKTEEDGAR SEEVEEKKAH MENGEKNVPE KTCENLVKIK
EEENGITREG KAASLLDSCT LVEGLLFPAE YYVRTTRRMT FSQSQPDMQA VILSQLSMGR
HRRSQGRGRG SNRDSQTRGS SDQHTQTDFS SPTTPSSFLN PLNSPQARPA DTAVECSQSS
GDTSNPVTAH QMDTPPVTVT RPPRGKRRRR RGRGRGRPQT SRAPQPPVSS VSSSQSVHEA
DGADTCLGPV KADSESGGTQ PSSTHSSSSK VNGAAERVQK VFPIFQKSSI TTSRQVNTGT
SNYQSLLLPS SSSPAQTSHL PPPPPLFPVP LVGSLKSLDT HQDFHLPDDQ FASLKLHKLR
QVAVESGVEH FSAPSHNTRS SFRCADSPCS IGDLTTLLSL PLSVTPTVTD PACPDDEEQQ
TQLRDLPSAH ILTDDLICKD STQEVFENNN PETNVEQQLH AETQDSEDCG HPEHEAVTPD
SQSRSCISTR STHRSTNSDK LNPQQSFLYK APFKGNDSVT GHSDELKEQL VAKKQTDYCG
LSSSSEDQMT RYHQVENRAA TETLLFDHSQ DETQEKPSNV PASLQTCNKA KVAHESPVQN
KNVQCSFDEP ELNPNLSEDR LTHCSQTVLK SPPASVNCSF RTTRPPSPAP APSPALPSLG
ITPHPPLSSS PAAPSLSLPP PHSPSTQALS PPALSPHPST PWLPPLSPCS HVQGSSEPPA
VSDRCHKVQL AASLNPSGGQ LHGSPGPGLQ TTEDTAEWCI MRRSHTLKAA AGGSLVDACC
LPGSSGGLFV AAAGKWAVCL WSQTSASDWS LKHTWTFREP VINVFPVPDA AGLICVTLGQ
LEIREVRTLS CRSLAETLIC EGVMQVVVGL YESRVVTSSH SATGSTLQAF TLSDSSGSWS
CQPLVSPGVC VGALAPVDEL SDALIGTSED GHLFIWNSKT GQLLCSVLLG HGLSHTACLR
GYSQSGVLLV LLQHHFLNSL DDDDDDEAII KDQMFSEEET KTALFSLVGI NPLSGKSVLA
TRLCPPKGWS GRLCEADVRR SSVVGLSQSG RICVWELGKQ TSRMVEAEDW QLVRWGGEDR
LVIGHHNGDV SLRCC
//
