ID A0A3Q3A7X4_KRYMA Unreviewed; 436 AA.
AC A0A3Q3A7X4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=EGF like repeats and discoidin domains 3 {ECO:0000313|Ensembl:ENSKMAP00000007014.1};
GN Name=EDIL3 {ECO:0000313|Ensembl:ENSKMAP00000007014.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000007014.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000007014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_017283402.1; XM_017427913.1.
DR AlphaFoldDB; A0A3Q3A7X4; -.
DR STRING; 37003.ENSKMAP00000007014; -.
DR Ensembl; ENSKMAT00000007130.1; ENSKMAP00000007014.1; ENSKMAG00000005304.1.
DR GeneID; 108242821; -.
DR KEGG; kmr:108242821; -.
DR CTD; 793444; -.
DR GeneTree; ENSGT00940000158144; -.
DR OrthoDB; 3043281at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR46806:SF10; EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 PRECURSOR; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS01286; FA58C_2; 2.
DR PROSITE; PS50022; FA58C_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..436
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018678420"
FT DOMAIN 30..73
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 75..111
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 114..270
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 275..432
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 63..72
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 101..110
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 436 AA; 49173 MW; 7D7A96C21A191E1D CRC64;
MGPLLPFFVL CWSAAVPHHV KGADGGEPTS AGPCHPNPCH NKGACEISET YRGDTFIGYV
CKCPPGFSGV HCQHNINECE RDPCKNRGIC TDLVANYSCD CPGEYMGRNC QYKCSGPLGM
EGGIISNQQI TASSTHRALF GLQKWYPYFA RLNKKGLVNA WTAAENDRWP WIQINLLRRM
RVTGLITQGA KRIGSPEYVK SYKVAYSDDG KTWRTYKVKG KEEDMIFRGN VDNNAPSANS
FTPPIEAQYV RIYPQVCRRH CTLRMELLGC ELTGCSEPLG MKSGHIQDYQ VTASSIFRTL
NMDMFTWEPG KARLDKQGKV NAWTAGRSDQ SQWLQVDLLL PTKVTGIITQ GAKDFGHVQF
VGSYKVAYSN DGERWSVYQD QKQGKDKVFQ GNFDNDTHRK NVIDPPIYAR FIRILPWSWY
GRITLRVEIL GCTEEE
//
