ID A0A3Q3AB44_KRYMA Unreviewed; 303 AA.
AC A0A3Q3AB44;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=SEC22 homolog C, vesicle trafficking protein {ECO:0000313|Ensembl:ENSKMAP00000013486.1};
GN Name=SEC22C {ECO:0000313|Ensembl:ENSKMAP00000013486.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000013486.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000013486.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in vesicle transport between the ER and the
CC Golgi complex. {ECO:0000256|ARBA:ARBA00003595}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR RefSeq; XP_017262062.1; XM_017406573.1.
DR AlphaFoldDB; A0A3Q3AB44; -.
DR STRING; 37003.ENSKMAP00000013486; -.
DR Ensembl; ENSKMAT00000013693.1; ENSKMAP00000013486.1; ENSKMAG00000010124.1.
DR GeneID; 108230404; -.
DR KEGG; kmr:108230404; -.
DR CTD; 9117; -.
DR GeneTree; ENSGT00940000159338; -.
DR OMA; QDRTNDC; -.
DR OrthoDB; 129635at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR043546; Sec22a/c.
DR PANTHER; PTHR46258; LONGIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46258:SF2; VESICLE-TRAFFICKING PROTEIN SEC22C; 1.
DR Pfam; PF13774; Longin; 1.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..303
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018730660"
FT TRANSMEM 221..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..119
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
SQ SEQUENCE 303 AA; 33442 MW; 60D5996E3FE25390 CRC64;
MSLILFAFVV RVRDGLPLSA STDFEHNREL QERKQQLRTI CRSLAGLSDR GTVKGQQLHI
YFTSSEGVSY MSVCHSSLPV AKAFCFLEDL RWEFTARFGG SAVTLAARPY PFLEFDSCIQ
KLKQQYNQTG GPALEVTLAE VQEDLRARPP QVIDLDEVAL TNGVANGHVE PSPASGKTLR
LEPVTPPGIL SLVLNIVCAS LNVIRGVHLV EHAIQDDNDG VWNVAAFLVA FVCCASQCHL
YLFHSSQKKL KSFFLLGAIV LCNSRLLGLR NAWQLAFHVS VASLSTFLTL ARKVQRRPDD
CGV
//
