ID   A0A3Q3AN55_KRYMA        Unreviewed;       806 AA.
AC   A0A3Q3AN55;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000018223.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000018223.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q3AN55; -.
DR   STRING; 37003.ENSKMAP00000018223; -.
DR   Ensembl; ENSKMAT00000018475.1; ENSKMAP00000018223.1; ENSKMAG00000013562.1.
DR   GeneTree; ENSGT00940000156136; -.
DR   OMA; FINYKTP; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.2300; -; 4.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF57586; TNF receptor-like; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..806
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018752145"
FT   TRANSMEM        534..557
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        569..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        604..629
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        649..670
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        691..715
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        727..746
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        753..775
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          535..797
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   806 AA;  91183 MW;  F8B63F372101FA47 CRC64;
     MKQAFVYLCL LGCFLLTKTV LASEFELDGD YWLGGLFDIH HVSEKLYHDR PETITCSSKP
     FILSSYRRFQ LMRFSVEEIN NSTSLLPNVT LGYKILDLCS DAQNFPGIFS LIFANGSIRP
     WDESLRKLSK MIAVVGTYTS TATLSVAPLF MMDHIPMVSY GAASSVFSRK QKFPSFLRTV
     HPNKDVIEVV LKILQEFDWR WVAFLYIEDD YGRDGQDLFI KEIESTDICL AYTKGLDPST
     NYPQMFRQLK SLTVNVYIVF APEWTAEALI KAAINQNVTN KVWIAGDAWS LHKQLPKEKG
     IRNIGTVIGI AEPVLPIPGF QDFISAFKGH SCNQNCNCSD VTADDIINAD PSFSFPVYSS
     VYAIAHALHA VLQCGAGKCN NSTKVYPHMV LTELQKSKFP LLNQTVQFDE NGDPMFGSYS
     IVFWNQSGEA EKVGFYNYYP FFQFSINTSK IKWHKDEEIV PVSLCSQECS NGSKKVQEGI
     HKCCFKCVPC PKGTYINSTG NQYKCTNCND TQWSATGSTS CKQRLVEYIR FKHGGAIAVM
     VWTLVFVGLN VAISILFAIN YNTPVVKSAG GPMCFLILAC LSLCSLSVFF SFGKPTTASC
     TLRLLPILLF FTVCLACFLV RSFQIVSIFK IAMTFPNFFN WWKKYHGQWL VITVVFVTQV
     ILIIIGYSIS PPKVQNKLHE DKILIACEFN IKAASGPLVL FSSLCFLSFC FSYVGKDLPK
     NYNEAKAITF CLLILILIWI TFYMIHQLYQ SEFIQVMLAV AVLSSLYTFL FWYFLPKCYI
     IIVQHNKNTQ QYFQSLIHSY ATTGNN
//