ID   A0A3Q3AN88_KRYMA        Unreviewed;       571 AA.
AC   A0A3Q3AN88;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Integrin alpha-11-like {ECO:0000313|Ensembl:ENSKMAP00000012924.1};
GN   Name=ITGA11 {ECO:0000313|Ensembl:ENSKMAP00000012924.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000012924.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000012924.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003762}; Single-
CC       pass type I membrane protein {ECO:0000256|RuleBase:RU003762}.
CC   -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC       {ECO:0000256|RuleBase:RU003762}.
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DR   AlphaFoldDB; A0A3Q3AN88; -.
DR   Ensembl; ENSKMAT00000013118.1; ENSKMAP00000012924.1; ENSKMAG00000009625.1.
DR   GeneTree; ENSGT00940000155465; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd01469; vWA_integrins_alpha_subunit; 1.
DR   Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR013517; FG-GAP.
DR   InterPro; IPR013519; Int_alpha_beta-p.
DR   InterPro; IPR000413; Integrin_alpha.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR   PANTHER; PTHR23220:SF21; INTEGRIN ALPHA-11; 1.
DR   Pfam; PF01839; FG-GAP; 1.
DR   Pfam; PF00092; VWA; 1.
DR   PRINTS; PR01185; INTEGRINA.
DR   PRINTS; PR00453; VWFADOMAIN.
DR   SMART; SM00191; Int_alpha; 3.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS51470; FG_GAP; 3.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cell adhesion {ECO:0000256|RuleBase:RU003762};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Integrin {ECO:0000256|RuleBase:RU003762};
KW   Membrane {ECO:0000256|RuleBase:RU003762};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Receptor {ECO:0000256|RuleBase:RU003762};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|RuleBase:RU003762};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU003762}.
FT   TRANSMEM        37..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU003762"
FT   DOMAIN          108..289
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REPEAT          298..349
FT                   /note="FG-GAP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT   REPEAT          403..464
FT                   /note="FG-GAP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT   REPEAT          472..530
FT                   /note="FG-GAP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
SQ   SEQUENCE   571 AA;  62952 MW;  C3BA2542AB19B966 CRC64;
     FEYTKKQQTG DVYKCPLNTR SSSNCSRLNI ATVSRTVLVL IHVFLICLFF FSSCICWNLL
     FPQTCGPLWS HECGSSLYST GVCTRTKQNF KLNQIIAPAL QRCETFMDIV IVLDGSNSIY
     PWYEVQNFII NILQKFYIGP GQTQVGIVQY GSTVVHEFSL GEYQTVEKVV EAARNIDQRG
     GEETRTALGI NVARSEAFRH GGRPGAQKVM IVVTDGESHD SPQLVQVVND SRKDNITTYA
     IAVLGNYNRR GINPESFLTE IKFIASDPDE EYFFEVTDEA ALKDIVDSLG ERIFSLEGYT
     QGKGFGLQMA QAGFSSCFVQ DGVLLGAVGA YDWNGAVLKE TKHGKIVPPK SSYKDDFCSL
     VLGYSLGSVI SSSGSQLYVA GAPRFNHTGK VIIFTMKNTG NLTILQALLG EQIGSYFGSE
     LLSMDIDSDG CTDFLMVAAP MFYSQDWERG RVYIYSLISE TKLSPQTSFI LQGLLEVSDQ
     SQNSRLGSAL AQIADMNGDG FQELVVGAPL EDNHQGAVYV FHSKDKKIQP HYKQVIISVK
     HQPQTKTTFL RLMGGAPLRL LGEGLGSAWG C
//