ID A0A3Q3AP48_KRYMA Unreviewed; 1090 AA.
AC A0A3Q3AP48;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Unconventional myosin-If-like {ECO:0000313|Ensembl:ENSKMAP00000018618.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000018618.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000018618.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR RefSeq; XP_017275874.1; XM_017420385.1.
DR AlphaFoldDB; A0A3Q3AP48; -.
DR STRING; 37003.ENSKMAP00000018618; -.
DR Ensembl; ENSKMAT00000018878.1; ENSKMAP00000018618.1; ENSKMAG00000013798.1.
DR GeneTree; ENSGT00940000158870; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF663; UNCONVENTIONAL MYOSIN-IF; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 15..688
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 726..915
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT DOMAIN 1033..1090
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 565..587
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 911..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1018
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 108..115
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1090 AA; 124625 MW; B6BE13575E2243C0 CRC64;
MKAKYHWQSQ NVKQSGVDDM VLLSKITEDA IVENLKKRYM DDYIFTYIGP VLISVNPFKQ
MPYFTDREVE LYQGAAQYEN PPHIYALTDN MYRNMMIDGE NQCVIISGES GAGKTVAAKY
IMGYISKVSG GGPKVQHVKD IILQSNPLLE AFGNAKTVRN NNSSRFGKYF EIQFSRGGEP
DGGKISNFLL EKSRVVSQNE SERNFHIYYQ LIEGASAQQK EGLGIMTPDY YYYLNQSGTY
KVDGTNDSKD FQETMEAMQV IGIPGDIQAQ VLQITAGILH LGNISFIEAG NYGQVESIDL
LAFPAYLLGI DPSRLQDKLT SRKMDSKWGG KSESINVTLN QEQATYTRDA LAKALYARLF
DYLVEAINKA IQKPHEEFSI GVLDIYGFEI FQRNGFEQFC INFVNEKLQQ IFIELTLKAE
QEEYVQEGIK WTPIEYFNNK IVCDLIENKL SPPGIMSVLD DVCATMHAKG EGADGTLLQK
LQAAVGTHEH FNSWNSGFVI HHYAGKVSYD INGFCERNRD VLFPDLIELM QSSEFDFIRS
LFPENLNTDK KGRPTTASSK IKRQANELVN TLMKCTPHYI RCIKPNETKR PKDWEESRVK
HQVEYLGLRE NIRVRRAGFA YRRLFNKFLM RYAILTPETW PCWRGPEQQG VLHLLRSVNM
DNDQYQMGRT KVFVKNPESL FLLEEMRERK FDTFARIIQK AWRRYNARKK YEQMREEASD
ILYNSKERRK NSINRNFVGD YLGLEQRPEL RQFLSKRERV DFADSVNKFD RRFKSIKRDL
ILTPKGIYLI GREKVKKGPE KGQIKEVLKR KLDFVNIAGV SLSARQDDFF VLHEAQYDSL
LESNFKTEFL SLLSKRYEEV TKSKLTISFS DRLEFRVKKE GWGGGSSRVV VFQRGPGDLA
QLKPAGKTLT VTIGDGLPKS SKPTRKSALD SRGRGRTHVP SSAHQNGGAK FSRAPPTRQS
EITYSSPHKQ NRPPSAALPK LGSQKAHRAP AHNQHNHSNL DFLNVPDQGM SGKQRKRSIS
SRPPPAPKPQ PRPQGPRCRA LYQYVGQDTD EISFDVDEVF DLVREDGSGW WTGRIRGKEG
LFPGNYVEKI
//
