ID   A0A3Q3AP52_KRYMA        Unreviewed;       800 AA.
AC   A0A3Q3AP52;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000018181.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000018181.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q3AP52; -.
DR   STRING; 37003.ENSKMAP00000018181; -.
DR   Ensembl; ENSKMAT00000018433.1; ENSKMAP00000018181.1; ENSKMAG00000013504.1.
DR   GeneTree; ENSGT00940000156136; -.
DR   OMA; THCENTE; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..800
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018749811"
FT   TRANSMEM        536..563
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        575..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        606..634
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        641..662
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        688..709
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        721..743
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        749..769
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          537..791
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   800 AA;  90302 MW;  276243D3095449F1 CRC64;
     MRDKQVLAYL GLLGCFLHVL MTGAMTASEF EMDGDYLIGG LFDIHHVSGT PYHDRPEAIT
     CSSQRWILSS YRRFHLMRFS VAEINNSTSL LPNVTVGYKI FDHCSDTLNF PGIFNLISVN
     GLVEPWDKSL KNLSKVIAAV GIFTSTDTLT VAPLFMIDLI PMVSYGAASS VFSKKQNFPS
     FLRTLHPNKD VIEVVFNILK KFNWRWVSFL YTEGDYGEDG LDLFMNKIKD TDICLAYTKG
     LNENTDYPQM FRHLEIQRVN INIVFAVEWT AEALIKAAIK QNVTNKVWIA GNAWSLHKQL
     PKEKGIRNIG TVLGIAEPVL TIPSFSDFVY SFKAKSQLEN ADQEKFCNQF SNYNTSAKDI
     INADPSFTFS VYSAVYAIAH ALHSVLQCGD GRCNRNISVQ PHMVLGALVR FDENGDPNYG
     SFSIFFWNQS GEAEDVGFYH FDSVFHFYIN TTRIQWHANR EVPASFCSQE CPVGYVKNQE
     GIHKCCFSCK ICSNGTYDNS TEDPYRCIDC KDTEWSAAGS TSCNLRLVEY VPFTDIGAVV
     IMVGTWIFIG LIIAVSVLFA INYNTPVVKS AGGPICFLIL VCLSLSDISV FFYFGEPTTA
     SCILRFLPFL MFYTVCLACF VVRSFQIVCI FKIWTKYNGQ WLIITVAFIT QAITLTIGYS
     IAPSKPFNDT MSYSKSIILG CDFNFEGIAA SLVLLLSLCC LCFIFSYMGK DLPKNYNEAK
     AITFCLLLLI LTWIIFATTN VLYHGKHIHT FNALAVLSSL YSFLLWYFLP KCYIIIFQPH
     KNTQQHFQGL LQNYTKTVSQ
//