ID A0A3Q3APX4_KRYMA Unreviewed; 1386 AA.
AC A0A3Q3APX4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSKMAP00000018380.1};
GN Name=ZNF521 {ECO:0000313|Ensembl:ENSKMAP00000018380.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000018380.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000018380.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSKMAT00000018637.1; ENSKMAP00000018380.1; ENSKMAG00000013661.1.
DR GeneTree; ENSGT00940000159287; -.
DR Proteomes; UP000264800; Unplaced.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR008598; Di19_Zn-bd.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR PANTHER; PTHR24406:SF30; ZINC FINGER PROTEIN 423; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF13912; zf-C2H2_6; 5.
DR Pfam; PF05605; zf-Di19; 1.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 9.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 26.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 23.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 143..170
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 171..198
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 199..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 272..300
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 310..338
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 340..367
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 508..536
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 544..567
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 663..685
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 693..715
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 723..747
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 751..779
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 781..809
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 812..839
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 838..861
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 929..956
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 973..1000
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1002..1029
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1213..1241
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1300..1327
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1331..1359
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1361..1386
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 874..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1234..1265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1386 AA; 154398 MW; BF53A6B395C4F17D CRC64;
MSRRKQAKPR SLKEDNVTED QHSPGQTAIP SDPECALERV AEDGEAGHLR KRLLSPEEGE
EGEEEDEEPA LHSCDSCRQV FESLSDLTEH KINQCQLTDG ADLEDDPSCS WPASSPSSKD
QTSPGHCEDY EFGEDEGGPG LPYPCQFCDK SFSRLSFLKR HEQSHGDKLP FSCTFCSRLF
KHKRSRDRHV KLHTGDKKYH CGECDSAFSR SDHLKIHMKT HASNKPHKCP VCRRGFLSSS
SLHGHMQVHE RGKDGSSSSF SRAEEWKLKE TRKCSRCEEG FDVPEELQRH IAECHPECSP
SEDGGLGATL QCIYCHEPFS DEGTLLTHID QAHSRDRKGH TCAICSEHFL SVEDLYAHMD
IHQLPESSNH SNSPSLLTVG YTSVSSTTPD SNLSVDSSTM VETAPPVAKT RGRRKRAAQN
ASDMGGRSSK QPKVSYSCIY CNKQVFSSLA VLQIHLRTMH LDKPEQAHTC QFCLEVLPSL
LNLNEHLKQI HNAEDHAALL ASLPDALLQC NFCPEVLSDL NALQEHIRCS HGFPSPVAKE
SNAFFCPQCF MGFLTEATLE EHVRQTHCDG GSLRFDSPLA VTPKEPIVEV YSCSYCTNSP
IFNSVLKLNK HIKENHKNIP LALNYINNGK KSLRTLSPSS PVSVEQTAML KQGSSASRAT
SEFICNQCGA KYTSLDLFQT HLKTHLDGLQ PQLTCPQCNK EFPNQESLLK HVTIHFTITS
TYYICESCDK QFTSVDDLQK HLLDMHTFVF FRCTLCQEVF DSKVSTQLHL AVKHSNEKKV
YRCTSCNWDF RHETDLQLHV KHSHLENQGR AHRCIFCGES FGTEVELQCH ITTHSKKYNC
RFCSKAFHAI VLLEKHLREK HCVFEGKSQN CGTNGSTVSG GEGQPKDDAE LQGLLTNSHG
PGAGGGSVVE SQNSHDGSEE EVDTAEPMYG CEICGASYTM ESLLTNHQLR DHNIRPGESA
MIKRKAEMIK GNHKCNVCSR TFFSEAGLRE HMQTHLGPVK HYMCPICGER FPSLLTLTEH
KVTHSKSLDT GSCRICKMPL QSEEDFLEHC QMHPDLRNSL TGFRCVVCMQ TVTSTLELKI
HGTFHMQKTG PMSSSQPLVR NNIMSQNQQP HHAQKFFKCA SCLKDFRSKQ DLVKLDINGL
PYGLCASCVT AAGSKSSSPT VNGGRQQQGG ATTPASTAAW VQGESLSPGD GKGKGVSSSS
SSSSTSSSSV IKTRCSSCNV KFESEAELQT HVQTVHREQG GDSNSGQLKT PQVSPMPRAS
PSQTEEKKTY QCIKCQMVFY SEWDIQVHVA NHMLEEGLNH ECKLCSQSFD SPAKLQCHLI
EHSFEGMGGT FKCPVCFTVF VQANKLQQHI FSAHGQEDKI YDCSQCPQKF FFQTELQNHT
LTQHSS
//
