ID A0A3Q3ARZ8_KRYMA Unreviewed; 1673 AA.
AC A0A3Q3ARZ8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313|Ensembl:ENSKMAP00000019286.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000019286.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000019286.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR STRING; 37003.ENSKMAP00000019286; -.
DR Ensembl; ENSKMAT00000019549.1; ENSKMAP00000019286.1; ENSKMAG00000014269.1.
DR GeneTree; ENSGT00940000154648; -.
DR OMA; EEGFYKW; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF10; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT DOMAIN 1364..1486
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1551..1673
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1117..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 955..986
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 8..64
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..360
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..654
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..674
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1673 AA; 184888 MW; 84CC484AEF998137 CRC64;
MNKAPQPITG PPSAPHPAPS PGLSQPSFPP GQPPSVVFAT PAPPQMNPTP QPRQFAPGPR
PMHQQPYYPN RASLPPSSGP RGIPPSSAPR PVTPTHVYQA GPGSQMMMIP QQQLSFASSP
QGPAYFIPGQ YRSPTYVATP QQYPVAAGTA GFYPGTSPAE YAGAYYPAQP QFTPPVQAAP
VIMNPAPQQQ PPPPQASQHI HTKRERKQIR IRDPNQGGRD ITDEIMSGGR SGSTPTPPQT
AISGSDSSAL PQANGESLTA AARPDDRGKH TPPPLSQTPE LAKTDPFPSE PTSSDTNTKA
PIPPPLSESK NEPLNTICTP APSASVTDVI DAPLPSRESS PTPQSGPEVP AYPAPLPNPF
PSSSAQNKMD LIIKEAEEEV VTGEESTLED ADASLAKSSA QPSSTNGVAE VELEKPSVTL
PPCHLEDPLE SPIAQPEELR LSNGLPLPAP QDPEAPVVST SEHDDSPIAE PDVSQQPVLL
TFVTEAAKQI VTASTVPADQ SAPTNIDEEV PVKAAVQPEP AQPEAQDMAP ETVLNVEENA
PLLQPNTREE TSSPAEPVST ADSMPETMPA PPPPTAEEKE DILATQIVTP TVVETTMQAA
VSVPKKKRKM KDLNKKEAVG DLLDAFKEEQ VVVRPEPEPA PTLEPKPPAA SPPAPEEADL
TWEDKEDKLD AENIQPDSQK PTSTDKKYQY KEEQWKPINT EEKKKYDREF LLGFQFISAS
MNKPEGLPAI SDVVLDKANK TPLHQLDPSR LPGMNCGPDF TPSFANLGRP GMGGGSRGPP
PGMGIGVGGP RRSQQVQRKE PRKIITSMSL NDDVQLNKAE KAWKPSLKKP TRSRVVEDVE
ESDPEQIKTQ ELFKRVRSIL NKLTPQKFQQ LMKQVQELTV DTEERLKGVI DLTFEKAISE
PDFSVAYANM CRCLSGLKVI TPDKPGFTVN FRKLLLNRCQ KEFEKDKDDD EIFEKKQKEL
EAASGEEEKQ RLIDELEEAK DKARRRSLGN IKFIGELFKL KMLTEVIMHD CIVKLLKNHD
EESLECLCRL LSTIGKDLDF EKAKPRMDQY FNQMEKIIKE RKTTSRIRFM LQDVLDLRRN
NWVPRRGDQG PKTIDQIHKE AELEEHREHM KVQQALISKK ESSGGPGGRM GGGPGSRGGP
HTPGRGAPPQ DEGWNTVPIS KNRPIDTSRL SKITKTPVLD FNNQLLAPGG KGTWGSWGKG
SSGGSSSAKP TDSSSESGSR PATSTLNRFS ALQQPSSLSG SSQDSDRRVP QRNSSSRERS
DRFEHSDRGG DRFDRRDERR DDRDRNRLQL TKRSFSREKD ERRESREKEQ TGSSDPVRRV
ASMTDAQDRG SRERTRSKEK VNQEAAAAPS PHQIPTKPSL TEGEVDKKST AIIEEYLHIN
DMKEALQCVR ELDSTELLFV FVRNGLESTL ERSTIAREHM GQLLHQLIKT GILPKQQYFK
GFQEILEVAE DMAIDIPHIF LYLAELITPM LHEGGIPMGE LFREISKSLV LVDKAGVLLV
HILTLLCKEM SHKKAGLMWR EAGLRWTDFL PEDVDINKFV TEKNVEFTLG DESEKSRKEM
SSAELTKQLE RLIQDQADNQ RIFDWVEANL DEQHTSSNVF VRALMTCICQ SAVICETPYK
VDGEQIKQRA KLLQRYLKDE QKELQALYAL QALMVQMEQP ASEHPHLLLV TER
//
