ID A0A3Q3AW28_KRYMA Unreviewed; 761 AA.
AC A0A3Q3AW28;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=BMP/retinoic acid-inducible neural-specific protein 1 {ECO:0000256|ARBA:ARBA00041019};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000021288.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000021288.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the BRINP family.
CC {ECO:0000256|ARBA:ARBA00010360}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017263375.1; XM_017407886.1.
DR AlphaFoldDB; A0A3Q3AW28; -.
DR STRING; 37003.ENSKMAP00000021288; -.
DR Ensembl; ENSKMAT00000021566.1; ENSKMAP00000021288.1; ENSKMAG00000015805.1.
DR GeneID; 108231056; -.
DR KEGG; kmr:108231056; -.
DR CTD; 1620; -.
DR GeneTree; ENSGT00940000158084; -.
DR OMA; MSESWAS; -.
DR OrthoDB; 3949486at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR CDD; cd00064; FU; 1.
DR InterPro; IPR033237; BRINP.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR15564:SF7; BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1; 1.
DR PANTHER; PTHR15564; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19052; BRINP; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022810};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..761
FT /note="BMP/retinoic acid-inducible neural-specific protein
FT 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018561617"
FT DOMAIN 72..251
FT /note="MACPF"
FT /evidence="ECO:0000259|SMART:SM00457"
SQ SEQUENCE 761 AA; 88742 MW; 95049C6A8A0222E0 CRC64;
MNWRFIEVIC FLFIWDHITV QSSRQDLLAA EQHVAKQYDW LISDRGPFHH SRSYLSFVER
FRQGFTTRYK IYREFARWKV RNTAIERRDL IRNPLPLMPE FQRSVRLLGR RPTTQQFIDT
IIKKYGTHIL ISATLGGEEA LTMYLAKNKL DRKLANATQN VEALHQLASS YFIDRDGTMR
KLHEIQISTN AIKVTETRTG PLGCSSYDNL DSVSSILLQS PESKLHLQGL QVIFPEYLQE
KFVQSALSYI MCNGEGEYVC QNNQCICQCA EDYPQCNCPI TDIQIMENTL LVMSESWAAS
YKDFENSDEF KSFLKRLPST HFLPISSVHL LWGSDWDLQA RYRLLQSSLE IQRLKIQRTA
RKLFSLSIRC HHNPSHQMPR ERSVMQWLNR VQSFLYCNEN GFWGTFLESQ RTCVCHTGVT
LCQRPIPCVI GGNNSCAMCS LANISQCGSC NKGYKLYRGR CEPQNVDSER SEQFISFETD
LDFQDLELKY LLQKMDSRLY IHTTFISNEI RLETFFDPRW RKRMSLTLKS NKNRMDYLHM
IIGLSMKICQ MRNSSIDPMF FVYVNPFSGS HSEGWSMPFG EHSYPRWEKI RLQNSQCFNW
TLLLGNRWKT FFETVHIYLR SRAKIPTGLR NDTGQGPVDL ADPNKRQIYI KISDIQVFGY
SLRFNADLLR SAVQQVNQSY TQGTQFYSSS SVMLLLLDIR DRINRLAPPS APGKPQLDLF
SCMLKHRLKL NNSEMIRVNH ALDMYSTEIL KQSDHLTAKL C
//
