ID   A0A3Q3AXQ3_KRYMA        Unreviewed;      1373 AA.
AC   A0A3Q3AXQ3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Astrotactin 2 {ECO:0000313|Ensembl:ENSKMAP00000021436.1};
GN   Name=ASTN2 {ECO:0000313|Ensembl:ENSKMAP00000021436.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000021436.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000021436.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_017263166.1; XM_017407677.1.
DR   Ensembl; ENSKMAT00000021715.1; ENSKMAP00000021436.1; ENSKMAG00000015878.1.
DR   GeneID; 108230990; -.
DR   KEGG; kmr:108230990; -.
DR   GeneTree; ENSGT00390000003140; -.
DR   OrthoDB; 4157619at2759; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001764; P:neuron migration; IEA:InterPro.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR040685; Annexin-like.
DR   InterPro; IPR045574; ASTN1_2_Fn3.
DR   InterPro; IPR045575; ASTN_1_2_N.
DR   InterPro; IPR040510; ASTN_2_hairpin.
DR   InterPro; IPR026995; Astrotactin.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR16592; -; 1.
DR   PANTHER; PTHR16592:SF2; ASTROTACTIN-2; 1.
DR   Pfam; PF18411; Annexin_2; 1.
DR   Pfam; PF19743; ASTN1_2_fn3; 1.
DR   Pfam; PF19441; ASTN_1_2_N; 1.
DR   Pfam; PF18577; ASTN_2_hairpin; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1373
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018739151"
FT   TRANSMEM        206..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        448..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          868..1069
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|SMART:SM00457"
FT   REGION          31..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          378..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          407..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1373 AA;  151532 MW;  78C6588B306B28AC CRC64;
     MARLSALHIR VLLAALLLTG SLTLRASKWA TPADEDGDKE GDEETPCEVK TVTVSTLPVL
     RENEFSFTGG AAGNVAGGGG SAAGAGGAAG GGGTGGGTGG GGGGAGAGAG AGAGGGGESR
     LLLFVRTDLP GRISVMDDLD NTALPYFTLE MSGTGEDISQ VHWKQQWLEN GTLYFHVSMT
     ESELILQTTQ PTAREPAHVL HEHMHLLHIS VMGGLIALLL LILLFTLVLY TRHRWCKRRR
     IPQKSASTEA THEIHYIPSV LLGPQGRDSY RGSRGTHQHG SSVIGMPIRE TPILDDYDCD
     EDDGGGHSLN STPNQLHNKI NDGKVLDDYG VNVGIGGHTD IMFKEDDIKH NFEKQAIEAN
     TESVEDLMQR FQDSFRVPNT PTNMSHYQHA VHSSSTGRRR VSSHIRATGG MYGPQGESGS
     EPEDDNQMKF YTEQNRGRRR SKGHSQSPLN KVTLTLITIS TCVIAIVYAT QDSCPLTVKV
     TLHVPEHFVA DGSSFVVSMG SFLDVSNWLN PAKLTLYYQT NSSTQWIRDY CGQRTTEPCE
     QICDQDTGEC SCHEGYSPDP AHKHLCVRSD WGRNEGPWPY ANLEKGYDLV TGQQAPERIF
     RSFYSLGQGL WLPVSKSFVV PPVELSINPI ASCKTDVLVT EDPGEVREEA LMSTYFETVQ
     DLLASFGPVR DCSKDNGGCK KNFKCVSDRQ LDSSGCMCPE GLRPMKDGSG CYDYSRGIDC
     TDGFNGGCEQ LCLQQLVPLE DDPSSSNVLM FCGCVQEYKL AGDGRSCLLQ SENCEGPKCP
     RQDVRFNDTL FGEMLHGYNN KTQQVNLGQI FQMTFRDNNF IKDFPQLADG LMVIPLPVEE
     QCRGILSEPL PNLQLLSGDA QFSEAVGYPM VQQWRVRSNL YKVKLSSITL STDFSKVLKT
     LSGESTREEL LAFLQEYGSH YVSEALYGSE LSCSIYFPSK KAQQQLWLQY QKEATEQGVG
     GGGRRELKSV PFINYLLALQ KSQLLVDDIV NGVEIRCEEK GSCPSGCHLC HHQTTVRGGA
     GRGGNNRSGE QPSPIPVLLE VSRVVPLYGL IQDNVTKEAF KSATMSSYWC AGKGDVIDNW
     CRCDLSAFSK DGLPNCSPLK QPILRLAPYL EPSSTTVALE WMDVEPLIGC KVSDYIIQHK
     RVEDPSEAEI YTGEVLSLMD DLFSGLSSSC VVAGRRSGDH PQSVVYSVVF KCLEPDSLYK
     FTLYAVDNRG SQTESSFVSV RTSCPVVDDS RAEEIADRVY NLYNGYTSGK EQQMAYNMLM
     EIPPPMLYRV QHHYNSHYEK FGDFVWRSED ELGPRKASLI LRRVDTISLY CRSLLRSTHI
     QSRTDTMAYI YCRSEEGRPP SNTWHSSLHD SRTSCMEKLI SVQRNTYSNT KLR
//