ID A0A3Q3AY84_KRYMA Unreviewed; 1484 AA.
AC A0A3Q3AY84;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Neurexin-1a-like {ECO:0000313|Ensembl:ENSKMAP00000016489.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000016489.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000016489.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_017291710.1; XM_017436221.1.
DR STRING; 37003.ENSKMAP00000016489; -.
DR Ensembl; ENSKMAT00000016722.1; ENSKMAP00000016489.1; ENSKMAG00000012218.1.
DR GeneID; 108247830; -.
DR KEGG; kmr:108247830; -.
DR CTD; 565531; -.
DR GeneTree; ENSGT00940000154292; -.
DR OrthoDB; 2999458at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00053; EGF; 1.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1484
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018567688"
FT TRANSMEM 1411..1431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..209
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 205..243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 266..456
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 463..658
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 662..699
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 704..877
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 891..1066
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1069..1106
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1110..1311
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1316..1401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1451..1484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1316..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1468..1484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1484 AA; 162496 MW; CC3735F9C3D184AD CRC64;
MSVMAVCVWA AAPLLFLGLC LCSVGGQAQG EVLEFGGVSS QWGRFPVWNA CCESVLSFSL
RTHSQEGLLL YLDDEGFCDF LELLLLHGHL RLRFSIFCAE PAELQSGVAV SDGRWHAVRV
KRDWRNTSLE VDGRLEGWAE VKSKRRDMTV FSHTYMGGLS SDLHSSPLRL TSPTVREHAA
FRGWITAVSI NGSLVTLDGS EGITVTAGCG PDHQCQNGGV CSVVNDQAIC DCSDTGYQGN
DCSEEHSYTP GLAHLMIGDQ AREEYVATFK GSEYFCYDLS PNPIQSSSDE ITLSFKTLQR
NGLMLHTGKS ADYVNLALKN GAVSLVINLG SGAFEALVEP VNGKFNDNTW HDVKVTRNLR
QHSGIGHAMV TISVDGILTT TGYTQEDYTM LGSDDFFYVG GSPSTADLPG SPVSNNFMGC
LKEVVYKNND VRLELSRLAK QGDPKMKVSG VVSFKCESVA TLDPVTFDTP ESYVALSKWT
AKKAGSISFD FRTTEPNGLM LFSHGKPRLQ LQHKDPRTPP TVKVDFFAIE MLDGHLYLLL
DMGSGTTKTK AIDRKVNDGE WYHVDFQRDG RSGTISVNSV RTAYTAPGDS EILDLDDTLY
LGGLPEDRAG LIFPTEVWTA LLNYGYVGCI RDLFVDGQSK DIRRLAEAQR AVGVKPSCSR
EPPKQCLSNP CQHNGVCREG WNRYVCDCSG TGYLGRSCER DATILSYDGS KFMKVQLPVV
MHTEAEDVSL RFRSQRAYGV LMATTSRNSA DTLRLELDGG RVRLTVNLDC IRINCTASKG
PETIFAGSGL NDNEWHTVRV VRRGKSLKLT VDDLQPVEGQ MAGDHTQLEF HNVETGIVTE
KRFMPAVPSN FIGHLQGLAL NGMPYIDLCK NGDIDYCELN AVIGYKSIVA DPITFRSRSS
FVTLPTLQAY YSMHLFMQFK TTSPDGLILF NRGDGNDFIV IELVKGYLHY ISDLGNGAHL
IKGNSNSPLN DNHWHNVHIS RDTNNLHTVK IDTKVTTQTT MGAKNLDLKG DLYIGGVTKE
MYRELPKLVH SREGFQGCLA TVDLNGRLPD LLADALATMG QVERGCEGPS TTCQEDSCSN
QGVCLQQWEG FTCDCSMTSY AGPLCNDAGT TYIFGRDGGM VVYTWPPNER PSTRADRLAL
GFSTQQKHAV LLRVDSASGL GDYLQLQVDK GNIRVVFNVG TDDINIEESS KFVNDGKYHI
VRFTRSGGNA TLQLDDLPVI ERYPSGNNDN ERLALARQRI PYRLGRVVDE WLLDKGRQLT
IFNSQTTVRV GGGEKGAPMF QGQLSGLYYN GLRILNMAAE GHPHIRVEGS ARLVGDMPSS
SITPQSSAAA GGNRSDSAPS ISDITTTTAT NRKQGETSKS ADDLLVASAE CPSDDEDIDP
CDLSSAGPPL PDVKYPGPSE VVRESSSTTG MVVGIVAAAA LCILILLYAM YKYRNRDEGS
YHVDESRNYI SNSATQPNGS AKDKPLGIAK ISKNKKNKDK EYYV
//
