ID   A0A3Q3AYC2_KRYMA        Unreviewed;       397 AA.
AC   A0A3Q3AYC2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Rho GTPase activating protein 1 {ECO:0000313|Ensembl:ENSKMAP00000016529.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000016529.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000016529.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3AYC2; -.
DR   Ensembl; ENSKMAT00000016762.1; ENSKMAP00000016529.1; ENSKMAG00000012300.1.
DR   GeneTree; ENSGT00940000165508; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR45808:SF6; RHO GTPASE-ACTIVATING PROTEIN 1; 1.
DR   PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          51..206
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000259|PROSITE:PS50191"
FT   DOMAIN          223..396
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
SQ   SEQUENCE   397 AA;  45106 MW;  5F883EEB4C90A5A4 CRC64;
     MSSDLLVDLG EDPATAQLGQ LKLTTIEDQQ WPTDVSQDFN AGSPHLPWDH PYYDIARHQI
     IEVAGDDNFG RKVIVFNACR MPPHHQLDHH KLLMYLKGTL DQYVESDYTL IYFHHGLTSE
     NKPSLSWLRD AYREFDRKYK KNIKALYIVH PTMFIKTLLI LFKPLISFKF GRKINYVSYL
     SELEAVVKCD QLMIPARVRE YDNKLRASLK PSAQPPTSPP RSPPLPNQVF GVPLAVLRQR
     DPDGDPVPVV MRDTISFLSE QGNANTKLSG GETVGFREME DVHLAAVILK TFLRELPEPL
     LTYQLYNDIV NFACKSEHIS LVESLPEENL ASLRYLITFL AQVSANSEVN KMTNSNLAVV
     FGPNLLWGRD NAMSLSAIGP INNFTRTLLD QQHLVFT
//