ID A0A3Q3B092_KRYMA Unreviewed; 231 AA.
AC A0A3Q3B092;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Modulator of macroautophagy TMEM150B-like {ECO:0000313|Ensembl:ENSKMAP00000022271.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000022271.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000022271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC Cytoplasmic vesicle, autophagosome membrane
CC {ECO:0000256|ARBA:ARBA00004542}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004542}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DRAM/TMEM150 family.
CC {ECO:0000256|ARBA:ARBA00006565}.
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DR AlphaFoldDB; A0A3Q3B092; -.
DR STRING; 37003.ENSKMAP00000022271; -.
DR Ensembl; ENSKMAT00000022556.1; ENSKMAP00000022271.1; ENSKMAG00000016528.1.
DR GeneTree; ENSGT01030000234578; -.
DR OMA; HSCCDDV; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0000421; C:autophagosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR PANTHER; PTHR21324; FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED; 1.
DR PANTHER; PTHR21324:SF3; MODULATOR OF MACROAUTOPHAGY TMEM150B; 1.
DR Pfam; PF10277; Frag1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..231
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018704496"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 231 AA; 25348 MW; A79F60A12A91D188 CRC64;
MWKFAILPVF LAVFGIGGIW TVECAGHPPQ SCLFAQTCNI LSVLITCVVV IRFQQAKDFG
YEGRANVAGL WMGSISAVGL SLTSNIQASV SLEIHCFGAV VAFVPGLAYF WVQMYLTYKA
QPSVDRPWVG PIRFILCVLC SAFLGSSILS LSVNCVHVLF LDFSFPVCFF NLWYESAGAT
SEWLAVVVFF LLFGLFAAEF RHVDYCRLTV QRPALESDCC AGSVETNSCA I
//
