ID A0A3Q3B539_KRYMA Unreviewed; 1189 AA.
AC A0A3Q3B539;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Myelin transcription factor 1-like {ECO:0000313|Ensembl:ENSKMAP00000024141.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000024141.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000024141.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR RefSeq; XP_017265159.1; XM_017409670.1.
DR RefSeq; XP_017265160.1; XM_017409671.1.
DR AlphaFoldDB; A0A3Q3B539; -.
DR Ensembl; ENSKMAT00000024446.1; ENSKMAP00000024141.1; ENSKMAG00000017881.1.
DR GeneID; 108232093; -.
DR KEGG; kmr:108232093; -.
DR GeneTree; ENSGT00940000156364; -.
DR OrthoDB; 3091993at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 7.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816:SF10; MYELIN TRANSCRIPTION FACTOR 1; 1.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR Pfam; PF08474; MYT1; 1.
DR Pfam; PF01530; zf-C2HC; 7.
DR SUPFAM; SSF103637; CCHHC domain; 7.
DR PROSITE; PS51802; ZF_CCHHC; 7.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 616..854
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1060..1122
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..226
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..306
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..352
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..419
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..815
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1189 AA; 132931 MW; 1E0A8E2CECFC0DFA CRC64;
MSQDTETRTR TRSKAVRVTA DQVGQDMKLE LSSCPTPGCD GKGHVSGRYS RHRSALGCPI
VKKRKLEKAE AEENQCAPKR RNQASKQAEE DSDSAEEEEQ KEDGAEDKDL IKDQKNNKEK
ILTELITSDS LVTTEDIERL GPLAEDTMNR SINSEMDVKP ERENSNEVKT DDDPHQDQTP
TKDEDTQPLE EYQPSELPLE ETAVIHQEET NDEDDEEPEE GTEEQEQQER QENFDEEREV
RRQIMRQENS DHQYSSGDYN LQAKESQEEE EEEEEEEEEE EEVEEQKEEE EEEEQKDEEE
EEETEVSTPF NMSPTTQEYE ATVSLREEKV RTLVTEEEED EEQEEEKEEE EDVRQEKEVS
VVVEEEEEDR DSSKTSLSTV VIEVRSEEDD DEEEEEEEEE EEEDEDEEDE DEEEGEELDH
VSEGSGITDD SENWDMTRGN LGLLEQAIAL KAEEVQGGQD SRSSPDYQPY SSSVKSSEST
SAARRTSHCS KDKKEVKCPT PGCDGTGHVT GLYPHHRSLS GCPHKDRIPP EILAMHENVL
KCPTPGCTGQ GHVNSNRNTH RSLSGCPIAA AAKLNKNQDK QVHLQAAATE PSSNSDRVLR
PMCFVKQLEI PQYGSYRPNT VTTTPRANLA KELEKYSKVS FDYASFDVQV FGKRMIIPKT
PSTANTSPKA FKSKSFPKAP SPSHCVSGSF PKPTLSSSGY DYSQDAEAAH MAATAILNLS
TRCWERPETL STQPREPCTK ESDIEVDENG TLDLSMKKTK REDMQSPDPS SSSSSSSQHV
GAMLSQVHTQ SDWDSPLDFT KSSEVKEEDH EEMEYTAPSY TSSDGEEDDQ ENLEDRKYPG
EVTTSSFKVK FQPKDSKKDI LVCPTPGCDG SGHITGNYAS HRSLSGCPLA DKSLRTLMAA
HTAELKCPTP GCDGSGHITG NYASHRSLSG CPRAKKGGVK TTPTKDDKED SELLKCPVPG
CDSLGHISGK YATHRSAYGC PLAAKRQREG LLNGAPFSWK AFKTEGPTCP TPGCDGSGHA
NGSFLTHRSL SGCPRASGNK KKAKLPGDEY ITAKFRASDV LDNDEDIKQL NKEINELSES
NSEMEADMIN LHTQISSMEK NLKNIEEENK QIEKRNEALF LELSGLSQAL IRSLANIRLP
TMQEPVSEQN FDSYVDTLTH MFTNKDCYQN PENRALLESI NQAVKGIEV
//
