ID A0A3Q3B9C6_KRYMA Unreviewed; 430 AA.
AC A0A3Q3B9C6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=GDNF family receptor alpha-4-like {ECO:0000313|Ensembl:ENSKMAP00000026303.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000026303.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000026303.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDNFR family.
CC {ECO:0000256|ARBA:ARBA00005961}.
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DR RefSeq; XP_017263519.1; XM_017408030.1.
DR AlphaFoldDB; A0A3Q3B9C6; -.
DR STRING; 37003.ENSKMAP00000026303; -.
DR Ensembl; ENSKMAT00000026641.1; ENSKMAP00000026303.1; ENSKMAG00000019509.1.
DR GeneID; 108231145; -.
DR KEGG; kmr:108231145; -.
DR CTD; 565651; -.
DR GeneTree; ENSGT00940000160491; -.
DR OMA; GTDCLVA; -.
DR OrthoDB; 3899332at2759; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR InterPro; IPR016017; GDNF/GAS1.
DR InterPro; IPR037193; GDNF_alpha.
DR InterPro; IPR003438; GDNF_rcpt.
DR PANTHER; PTHR10269:SF2; GDNF FAMILY RECEPTOR ALPHA-4; 1.
DR PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR Pfam; PF02351; GDNF; 3.
DR PRINTS; PR01316; GDNFRECEPTOR.
DR SMART; SM00907; GDNF; 3.
DR SUPFAM; SSF110035; GDNF receptor-like; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..430
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018715105"
FT DOMAIN 26..105
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 145..225
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 235..329
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT REGION 346..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 46962 MW; 951237A19DFCE312 CRC64;
MDLWGVHLFL LITFALLDVI LAGTDCLVAG DSCSSDETCS PRLRTLRQCV AGDGSMKLGP
GARSQCANAV SALLSSPLHG CQCKRGMKKE KNCLSIYWSL HQSIIHGLNL VESYPYETVQ
RDYDYVRLAS ITADSDVGTT TVNRCLDAAK ACNVDDLCQK LRTEYVSACI KPSAKSGLCN
RPKCNKALRR FFDRVPADYT HQLLFCPCTD TACAERRRQT IVPSCSYETV DKPNCIAYMR
ICKADYVCRS RLAQFQYDCE PSETSANGCK QGNYGACLLA YTGLIGSTIT PNYVDNSTSN
VAPWCSCSAS GSTREECDHF LGYFTDNICL KNALVMFGSE SDQQSILKQT STPTHGRGEN
RSSTSQPETF KTMSNILDPV IPTQILGNEL LVGLATLPSD GLPNSASSHK LMLKAALSLV
LSLLHLLYGQ
//
