ID A0A3Q3BDJ8_KRYMA Unreviewed; 3603 AA.
AC A0A3Q3BDJ8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=CUB and sushi domain-containing protein 3-like {ECO:0000313|Ensembl:ENSKMAP00000028133.1};
GN Name=CSMD3 {ECO:0000313|Ensembl:ENSKMAP00000028133.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000028133.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000028133.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR Ensembl; ENSKMAT00000028486.1; ENSKMAP00000028133.1; ENSKMAG00000020709.1.
DR GeneTree; ENSGT00940000155549; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 28.
DR CDD; cd00041; CUB; 14.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 14.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 14.
DR Pfam; PF00084; Sushi; 28.
DR SMART; SM00032; CCP; 28.
DR SMART; SM00042; CUB; 14.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 28.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 14.
DR PROSITE; PS01180; CUB; 14.
DR PROSITE; PS50923; SUSHI; 28.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3527..3548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..175
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 178..239
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 243..341
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 379..440
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 443..554
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 557..614
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 616..724
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 727..788
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 790..898
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 903..960
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 962..1072
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1075..1134
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1136..1244
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1247..1307
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1309..1418
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1421..1481
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1483..1591
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1594..1655
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1657..1765
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1771..1832
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1834..1942
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1945..2004
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2006..2114
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2117..2176
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2178..2285
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2288..2349
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2351..2462
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2462..2524
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2525..2586
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2587..2651
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2652..2709
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2710..2767
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2768..2825
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2826..2887
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2888..2945
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2949..3007
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3008..3066
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3067..3127
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3128..3185
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3186..3243
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3247..3305
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3306..3365
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 585..612
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 931..958
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1309..1336
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 2680..2707
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2738..2765
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2796..2823
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2858..2885
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2916..2943
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2978..3005
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3037..3064
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3069..3112
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3156..3183
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3214..3241
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3276..3303
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 3603 AA; 394281 MW; D01F339BB0698047 CRC64;
MKGILSSRDG RYDGSVELRD VFNRRCVKCG RGDLVQGRTM RIRTGMVFWN LFFSLMFTCV
KGFIHTCGGT LKGRNGTIES PGFPYGYPNG ANCTWVIVAE EGNRIHIVFQ SFAVEEEYDF
LSLYDGHPHP ANFRTRLTGF TIPPPVTSSG SIFSLRLTSD FAVSAHGFKV AYEELRSSSC
GNPGVPPKGI LNGTQFNIGD KIRYRCVTGY VLDGHSLLTC VTSAAGVSVW DFPVPICRAE
DTCGGTLRGS SGLISSLGSS GECKWTILAD PGDTISLVFT EFQMEEKSDY LEIEGSEPPT
IWLTGMNIPA PIISNKNWLR LHFVTESNHR HKGFRAQYQG KVLHFSGELK SRGVKLLPGK
DNTNKLSLMN EGGIKQVSNY CPDPGEPENG KRIGSDFSIG ATAQFTCDED HVLQGSKTIT
CQRVAEVFAA WSDHRPVCKV KTCGSNLHGP SGTFTSPNFP IQYESNSQCV WIITASDPNK
VIQINFEEFD LEIGYDSLTI GDGGEVGDSK TIIQVLTGSF VPDLIVSMSH QMWLHLQSDE
SVGSIGFKIN YKEIDKESCG DPGTPLYGYQ EGSGFLNGDV LRFECQFGFE LIGERMITCQ
NNNQWSANIP ICIFPCFSNF TAPMGTVLSP DYPEGYGNNL NCVWLIIAEP GSRIHLAFND
FDLEPPYDFL TIKDGDQSGA TILGRFSGAE VPSHLTSNSN VLQLEFQADH SMSGRGFNIT
YSTFGHNECP DPGIPLNGRR FGDSFQLGSS ISVVCEEGFI KTQGADTITC HLEEGKVMWS
GLIPKCEAPC GGHYSGPSGV ILSPGWPGYY KDSLSCEWVI EAELGRSIKI SFDRFQTELS
YDFLEVHDGP NLLSPLIGSF NGTQVPQFLF SSSNFLYLLF TTDNSRSNSG FKIFYEVVTL
DTYSCMDPGI PVNGVRLNHD LSIGSTVSFQ CDPGYRLSHE EPLVCEKNHF WSHSLPTCDA
SCGGDIRGPS GIILSPGYPE LYPNSLNCTW TVEVNHGKGV QFTFHSFHLE DHHDYLLITE
NGSFAQPLAR LTGSERPSPV NAGLYGNFKA QLRFISDFSI SLQGFNISFS EYNLEPCQDP
GTPQFGWHTG SRFGIGDSLS FYCNTGYRLQ GAREIVCLGG GRRMWSAPLP RCVAECGSTV
SNNEGVLLSP NYPMNYDNSH ECVYSIQVQT GKGINITAST FQLAQGDILK LYDGKDGTAP
LLGTYTGTMM QGLSLTSTSN YLWLEFYSDQ ESTAAGFRLI YQSFELSHCD DPGVPQFGFK
ISDQGHFAGS SITFGCEQGY TLHGSALLKC MTGERRAWDN NLPSCIAECG GSFKGQSTGR
ILSPGYPFPY DNNLRCTWTI EVNSGNIVSL QFLAFDTEAS HDILKVWDGP PENEMSLKEV
SGSLLPEGIH STLNVVTIQF ETDFYITKSG FAIDFSSSLA TACRDPGIPM NGSRNGEGRE
PGDSVTFSCD PGYELQGESK ITCIQVENRY YWQPSPPSCI APCGGNVTGS SGFILSPNYP
HPYPHSKDCD WLITVHSDYV ISLAFISFSI EPNYDFLYIY DGPDSSAHLI GSFQDSKLPE
KIESTSNFMY LAFRSDGSVS YTGFHLEYKA KLREACFDPG NVMNGTRMGT DYKLGSMVTF
HCEAGYLLQG HSTLTCVMGN SKRPEWDRAK PSCQAPCGGH FTGSEGTVLS PNYPHNYTRG
QSCVYDIFVP GDFVLFGQFV VFQTLPSDVV EIYDGASADS VLLSSIYGSH SGETLPLSSG
NKITLKFTTN GTETAKGFHF VYQAVPRTSA TQCSSVPEPR FGKRIGNDFG IGMVVLFECN
PGYTLHGSNT IRCEAVPNAL AQWNGTVPTC VVPCGGVLTE RRGTILSPGY PEPYSNYLNC
AWRISVPEGA GIQIQVVTFA TEHNWDSLDF FDGVDANAPR LGSYSGTTIP QLLNSTSNNL
HLTFQSDISV SAAGFHLEYT AIGLDSCPEP MPPSNGHKVG DRYTVGDMVS FQCDQGFSLQ
GNAYITCMPG PVRRWNYPVP LCIAQCGGSM TDFSSVILSP GFPGNYQSSL DCTWRVQLPV
GFGIHLQFLN FSTEPVHDYL EVRSGTLETG TVIDRFSGPV VPNSLFSTTH ETTLFFHSDY
SQNKPGFHIV YQAYELQRCP DPRPFRNGIV IGQDYSVGMT ISFECLPGYT LLGEPSLTCL
HGVSRNWNHP MPRCEALCGG NITSMNGTIY SPGHPAEYPH FQDCMWTVRV PPGYGIYINF
SVINTEPIYD YITVWDGPDQ SSPQIGQFSG SSAQEGVSTT ANQVLIKFHS DFSTSGFFEL
HYYAYQLRTC QPPPPVANAT ILTDDDEFEI GDIIRYSCLP GFTLVGSEIL TCRLGERLQM
DGPPPVCQVQ CPAHEVRFDS TGVILSPGYP ENYPNLQMCS WLINVEKGYN ITLHFELFET
EKEFDILEIF DGPNIYSQSL STLSGDIETP FNLTTTGHQL LLRWSSDHGT NRRGFHIRYV
AMYCSTPDSP QHGFVVSQTG GHLNSMVRWA CDRGYKLIGK GSAVCKKTTY DYFSWDAPVP
ACQAVSCGVP TAPVNGGVLA ADYSVGTRVT YFCNSGYRLS SKELTTTVCQ PDGTWSNHNK
IPRCIVMTCP SLSSFSLDHG RWRIVNGSHY EFGTKIIFTC NPGYYRVGPA HIQCLANGVW
SWRNERPRCR IISCGDLPTP PNGKKIGTQT TFGASAIFSC NLGYVLTGST VRECLLSGLW
SGMETRCLAG HCGVPEPIVN GQVIGENFGY RDTVVYQCNP GFRLIGSSVR ICQQDHTWSG
HLPVCISVTC GHPGSPIYGR TTGDGFNYND VVRFSCNKGY TLEGPSTAQC QANRQWSQQP
PTCRVVNCTD PGIPANSIRE SKIEHGNFTF GSVVFYDCNP GYYLFGSSVL SCQPMGHWDK
PLPECIEVDC GHPGTPPYAV MIGDKFTFGS TVRYSCLGDR QLIGDSSLTC QLNGHWSGPL
PHCSGDSSGT CGDPGTPAHA SREVVGNFKV RSKVRFTCAV GHTLYGSAER ICFPNGTWSG
KQPFCKPVQC GNPGTPAHGR ISRVDGTTFS HSIVYSCTEG YFLTGSPTRQ CLANGTWSGT
APNCTMITCG EPGVPANGLR FGDDATVGQN VTFMCQPGYV MVGGENMISR TCTNNGTWSG
AMPICQVVTC PTPPSIPNGL LEGSVLEWGA SVSYSCLPGY ELSFPAVLTC TGNGTWSGDL
PQCLPKFCGD PGVPARGRRE GRSFIFKSDV TFTCSIPYML VGSATRMCQD DGTWSGSQPR
CIEPTRTTCE NPGTPEHGFM NYTTGFKVGS RVDFQCQQGH ILQGSTTRLC LPDLTWTGVQ
PACTPHSCKQ PRSPANADVM GLDLPSYGYT LVYTCQPGYF LSGGSEHRVC RSDGSWTGKV
PVCRVGSKSH EKIVKPVAGT PSPKLKVPDD VFAPDFIWKG SYDYKGQKQP MSLTVTSFNA
TNGKVNVTLT DSSMEFLLSG VYKRQEARLM LLLYQMRALA YSSLNRITDE NWTMDGFVSA
EPEGGSYVFQ GFIQGKDYGQ FGLQRLGKEN VTLPDLETNG STNSSSVAVA ILVPFFALIF
AGLGFYLYKQ RKTDKAQYTG CSVHENNNGQ ATFENPMYNT NTKAAEGKVV RFDPNLNTIC
TMV
//
