ID A0A3Q3BE94_KRYMA Unreviewed; 3542 AA.
AC A0A3Q3BE94;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=CUB and sushi domain-containing protein 3-like {ECO:0000313|Ensembl:ENSKMAP00000027950.1};
GN Name=CSMD3 {ECO:0000313|Ensembl:ENSKMAP00000027950.1};
OS Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000027950.1, ECO:0000313|Proteomes:UP000264800};
RN [1] {ECO:0000313|Ensembl:ENSKMAP00000027950.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR Ensembl; ENSKMAT00000028304.1; ENSKMAP00000027950.1; ENSKMAG00000020709.1.
DR GeneTree; ENSGT00940000155549; -.
DR OMA; PSCKWTI; -.
DR Proteomes; UP000264800; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 28.
DR CDD; cd00041; CUB; 14.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 14.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 14.
DR Pfam; PF00084; Sushi; 28.
DR SMART; SM00032; CCP; 28.
DR SMART; SM00042; CUB; 14.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 28.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 14.
DR PROSITE; PS01180; CUB; 14.
DR PROSITE; PS50923; SUSHI; 28.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264800};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..175
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 178..239
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 243..360
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 395..456
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 459..570
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 573..630
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 632..740
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 743..804
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 806..914
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 919..976
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 978..1088
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1091..1150
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1152..1260
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1263..1323
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1325..1434
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1437..1497
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1499..1607
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1610..1671
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1673..1781
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1787..1848
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1850..1958
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1961..2020
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2022..2130
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2133..2192
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2194..2301
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2304..2365
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2367..2478
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2482..2544
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2545..2606
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2607..2671
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2672..2729
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2730..2787
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2788..2845
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2846..2907
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2908..2965
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2969..3027
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3028..3086
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3087..3147
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3148..3205
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3206..3263
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3267..3325
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3326..3385
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 601..628
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 947..974
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1325..1352
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 2700..2727
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2758..2785
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2816..2843
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2878..2905
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2936..2963
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2998..3025
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3057..3084
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3089..3132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3176..3203
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3234..3261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3296..3323
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 3542 AA; 387171 MW; 0A1A70733B092800 CRC64;
MKGILSSRDG RYDGSVELRD VFNRRCVKCG RGDLVQGRTM RIRTGMVFWN LFFSLMFTCV
KGFIHTCGGT LKGRNGTIES PGFPYGYPNG ANCTWVIVAE EGNRIHIVFQ SFAVEEEYDF
LSLYDGHPHP ANFRTRLTGF TIPPPVTSSG SIFSLRLTSD FAVSAHGFKV AYEELRSSSC
GNPGVPPKGI LNGTQFNIGD KIRYRCVTGY VLDGHSLLTC VTSAAGVSVW DFPVPICRAE
DTCGGTLRGS SGLISSFDFP GGDSPGTGGG GGAGGLGSSG ECKWTILADP GDTISLVFTE
FQMEEKSDYL EIEGSEPPTI WLTGMNIPAP IISNKNWLRL HFVTESNHRH KGFRAQYQVK
SSGELKSRGV KLLPGKDNTN KLSLMNEGGI KQVSNYCPDP GEPENGKRIG SDFSIGATAQ
FTCDEDHVLQ GSKTITCQRV AEVFAAWSDH RPVCKVKTCG SNLHGPSGTF TSPNFPIQYE
SNSQCVWIIT ASDPNKVIQI NFEEFDLEIG YDSLTIGDGG EVGDSKTIIQ VLTGSFVPDL
IVSMSHQMWL HLQSDESVGS IGFKINYKEI DKESCGDPGT PLYGYQEGSG FLNGDVLRFE
CQFGFELIGE RMITCQNNNQ WSANIPICIF PCFSNFTAPM GTVLSPDYPE GYGNNLNCVW
LIIAEPGSRI HLAFNDFDLE PPYDFLTIKD GDQSGATILG RFSGAEVPSH LTSNSNVLQL
EFQADHSMSG RGFNITYSTF GHNECPDPGI PLNGRRFGDS FQLGSSISVV CEEGFIKTQG
ADTITCHLEE GKVMWSGLIP KCEAPCGGHY SGPSGVILSP GWPGYYKDSL SCEWVIEAEL
GRSIKISFDR FQTELSYDFL EVHDGPNLLS PLIGSFNGTQ VPQFLFSSSN FLYLLFTTDN
SRSNSGFKIF YEVVTLDTYS CMDPGIPVNG VRLNHDLSIG STVSFQCDPG YRLSHEEPLV
CEKNHFWSHS LPTCDASCGG DIRGPSGIIL SPGYPELYPN SLNCTWTVEV NHGKGVQFTF
HSFHLEDHHD YLLITENGSF AQPLARLTGS ERPSPVNAGL YGNFKAQLRF ISDFSISLQG
FNISFSEYNL EPCQDPGTPQ FGWHTGSRFG IGDSLSFYCN TGYRLQGARE IVCLGGGRRM
WSAPLPRCVA ECGSTVSNNE GVLLSPNYPM NYDNSHECVY SIQVQTGKGI NITASTFQLA
QGDILKLYDG KDGTAPLLGT YTGTMMQGLS LTSTSNYLWL EFYSDQESTA AGFRLIYQSF
ELSHCDDPGV PQFGFKISDQ GHFAGSSITF GCEQGYTLHG SALLKCMTGE RRAWDNNLPS
CIAECGGSFK GQSTGRILSP GYPFPYDNNL RCTWTIEVNS GNIVSLQFLA FDTEASHDIL
KVWDGPPENE MSLKEVSGSL LPEGIHSTLN VVTIQFETDF YITKSGFAID FSSSLATACR
DPGIPMNGSR NGEGREPGDS VTFSCDPGYE LQGESKITCI QVENRYYWQP SPPSCIAPCG
GNVTGSSGFI LSPNYPHPYP HSKDCDWLIT VHSDYVISLA FISFSIEPNY DFLYIYDGPD
SSAHLIGSFQ DSKLPEKIES TSNFMYLAFR SDGSVSYTGF HLEYKAKLRE ACFDPGNVMN
GTRMGTDYKL GSMVTFHCEA GYLLQGHSTL TCVMGNSKRP EWDRAKPSCQ APCGGHFTGS
EGTVLSPNYP HNYTRGQSCV YDIFVPGDFV LFGQFVVFQT LPSDVVEIYD GASADSVLLS
SIYGSHSGET LPLSSGNKIT LKFTTNGTET AKGFHFVYQA VPRTSATQCS SVPEPRFGKR
IGNDFGIGMV VLFECNPGYT LHGSNTIRCE AVPNALAQWN GTVPTCVVPC GGVLTERRGT
ILSPGYPEPY SNYLNCAWRI SVPEGAGIQI QVVTFATEHN WDSLDFFDGV DANAPRLGSY
SGTTIPQLLN STSNNLHLTF QSDISVSAAG FHLEYTAIGL DSCPEPMPPS NGHKVGDRYT
VGDMVSFQCD QGFSLQGNAY ITCMPGPVRR WNYPVPLCIA QCGGSMTDFS SVILSPGFPG
NYQSSLDCTW RVQLPVGFGI HLQFLNFSTE PVHDYLEVRS GTLETGTVID RFSGPVVPNS
LFSTTHETTL FFHSDYSQNK PGFHIVYQAY ELQRCPDPRP FRNGIVIGQD YSVGMTISFE
CLPGYTLLGE PSLTCLHGVS RNWNHPMPRC EALCGGNITS MNGTIYSPGH PAEYPHFQDC
MWTVRVPPGY GIYINFSVIN TEPIYDYITV WDGPDQSSPQ IGQFSGSSAQ EGVSTTANQV
LIKFHSDFST SGFFELHYYA YQLRTCQPPP PVANATILTD DDEFEIGDII RYSCLPGFTL
VGSEILTCRL GERLQMDGPP PVCQVQCPAH EVRFDSTGVI LSPGYPENYP NLQMCSWLIN
VEKGYNITLH FELFETEKEF DILEIFDGPN IYSQSLSTLS GDIETPFNLT TTGHQLLLRW
SSDHGTNRRG FHIRYVGEYQ TMYCSTPDSP QHGFVVSQTG GHLNSMVRWA CDRGYKLIGK
GSAVCKKTTY DYFSWDAPVP ACQAVSCGVP TAPVNGGVLA ADYSVGTRVT YFCNSGYRLS
SKELTTTVCQ PDGTWSNHNK IPRCIVMTCP SLSSFSLDHG RWRIVNGSHY EFGTKIIFTC
NPGYYRVGPA HIQCLANGVW SWRNERPRCR IISCGDLPTP PNGKKIGTQT TFGASAIFSC
NLGYVLTGST VRECLLSGLW SGMETRCLAG HCGVPEPIVN GQVIGENFGY RDTVVYQCNP
GFRLIGSSVR ICQQDHTWSG HLPVCISVTC GHPGSPIYGR TTGDGFNYND VVRFSCNKGY
TLEGPSTAQC QANRQWSQQP PTCRVVNCTD PGIPANSIRE SKIEHGNFTF GSVVFYDCNP
GYYLFGSSVL SCQPMGHWDK PLPECIEVDC GHPGTPPYAV MIGDKFTFGS TVRYSCLGDR
QLIGDSSLTC QLNGHWSGPL PHCSGDSSGT CGDPGTPAHA SREVVGNFKV RSKVRFTCAV
GHTLYGSAER ICFPNGTWSG KQPFCKPVQC GNPGTPAHGR ISRVDGTTFS HSIVYSCTEG
YFLTGSPTRQ CLANGTWSGT APNCTMITCG EPGVPANGLR FGDDATVGQN VTFMCQPGYV
MVGGENMISR TCTNNGTWSG AMPICQVVTC PTPPSIPNGL LEGSVLEWGA SVSYSCLPGY
ELSFPAVLTC TGNGTWSGDL PQCLPKFCGD PGVPARGRRE GRSFIFKSDV TFTCSIPYML
VGSATRMCQD DGTWSGSQPR CIEPTRTTCE NPGTPEHGFM NYTTGFKVGS RVDFQCQQGH
ILQGSTTRLC LPDLTWTGVQ PACTPHSCKQ PRSPANADVM GLDLPSYGYT LVYTCQPGYF
LSGGSEHRVC RSDGSWTGKV PVCRVGSKSH EKIVKPVAGT PSPKLKVPDD VFAPDFIWKG
SYDYKGQKQP MSLTVTSFNA TNGKVNVTLT DSSMEFLLSG VYKRQEARLM LLLYQMRALA
YSSLNRITDE NWTMDGFVSA EPEGGSYVFQ GFIQGKDYGQ FGLQRLESPI EANEGYMSSL
WS
//
