ID   A0A3Q3BGH4_HAPBU        Unreviewed;      1169 AA.
AC   A0A3Q3BGH4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DNA helicase MCM9 {ECO:0000256|ARBA:ARBA00041085};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE   AltName: Full=Minichromosome maintenance 9 {ECO:0000256|ARBA:ARBA00042301};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000000161.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000000161.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC       ECO:0000256|RuleBase:RU004070}.
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DR   RefSeq; XP_005940673.1; XM_005940611.2.
DR   AlphaFoldDB; A0A3Q3BGH4; -.
DR   STRING; 8153.ENSHBUP00000000161; -.
DR   Ensembl; ENSHBUT00000015961.1; ENSHBUP00000000161.1; ENSHBUG00000001321.1.
DR   GeneID; 102302191; -.
DR   CTD; 254394; -.
DR   GeneTree; ENSGT01050000244824; -.
DR   OMA; MSEDANC; -.
DR   OrthoDB; 1342948at2759; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR   CDD; cd17760; MCM9; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR031327; MCM.
DR   InterPro; IPR001208; MCM_dom.
DR   InterPro; IPR041562; MCM_lid.
DR   InterPro; IPR033762; MCM_OB.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11630:SF48; DNA HELICASE MCM9; 1.
DR   PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR   Pfam; PF00493; MCM; 1.
DR   Pfam; PF17855; MCM_lid; 1.
DR   Pfam; PF17207; MCM_OB; 1.
DR   PRINTS; PR01657; MCMFAMILY.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00350; MCM; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50051; MCM_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004070};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          312..515
FT                   /note="MCM"
FT                   /evidence="ECO:0000259|PROSITE:PS50051"
FT   REGION          661..756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..756
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1169 AA;  130214 MW;  EE6C56D8F174FBB8 CRC64;
     MLISPEQEAL IDRVFETYLT DHHHNDILQL IEETEDNEDT HRPLVVNAMT LFEANMEIGD
     YFNAYPTDIL AIFDKVLNRK AKAVTDDGSL KHNEGQRKQD QRLVHTLHAR ITGLPVCPEL
     TRDTIPRTRD VGHFLSVTGT VIRTSIAKVL EYERDYMCTK CRHVFTVQAE FEQFYTFVPP
     VACPNPDSCN SYKFTCLSEG SEPAACRDYQ EIKIQEQVQK LSVGSIPRSL LVVLENDLVD
     SCKSGDDVTV YGVMCLRWKT FYDGALCDVE LVLKANNIEV NNQQAAAGQL VKDAQEEFEE
     FWNSYKHNPI AGRNHILLSL CPQVFGMYVI KLAVAMVLAG GVQRIDSSGT KIRGECHMLL
     VGDPGTGKSQ FLKYAAKIMC RSVLTAGIGS TSAGLTVAAV KDGGDWHLEA GALVLADGGL
     CCIDEFNSIK EQDRISIHEA MEQQSISVAK AGMVCKLNTR TTILAATNPK GQYDPNEPLS
     VNVALASPLL SRFDLVLVLL DTRNAEWDHI ISSFIMEDRG LPDQCSSLWS MEKMKAYFSL
     IKHLKPVMSE DANCILTRYY QLQRRSDGSS AARTTIRTLE SLSRLAEAHA KLMYRETVTI
     EDAVIAVSVM ECSMQGGALQ GNVNTLFTSF PADPVEQYQT QCQILLEGLN LPLFLKKERD
     RLSRSKSQTS ESPECDSSTT KLKHLLSDAN SKTHTSNLES GNTVRSDSNW FHTSLSLSPN
     DRTSPITTPQ ENTKTISSGT DVSKVTRQSS CRSEKLTSRR TVAPVVFGNI TSVSEQNIQG
     KKNESVTEEI SKSQEEILKY ERKKHEAHPE PLGYHFQKVS RSTMDSKNMG DKGFGQLDLK
     HQRFHKEVGK GHRERLVFGD ESENVLETNL STDKDSYVKE DKLHLTESRK SSAVPREKMA
     VEAETHIDLR GKLSRFMFKP SKMRTSVDNH NNNASPEKQM TVSVNTKKPI SHNDAHLCQR
     TRVSTGDDRD IFTSTPLSKS SACITNQTTL QSEQMKTSIT SSSSEIKLSG FSSIWTSEPT
     TAQTKMENST LKKGDADCLR ANSKVHKILN IANHIGKKCQ TIPPATDYTP AKKCELGMKS
     TSTTMSECKV KQTEFSHTEN NTVKMVTRDS VNCQRTASLK RKCFTSPQDS NSSGSKGLFS
     GLSLFESAEL NNDVLDTDWD QEVLKKAKV
//