ID   A0A3Q3BGI0_KRYMA        Unreviewed;       936 AA.
AC   A0A3Q3BGI0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Rho GTPase-activating protein 39-like {ECO:0000313|Ensembl:ENSKMAP00000028890.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000028890.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000028890.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3BGI0; -.
DR   Ensembl; ENSKMAT00000029253.1; ENSKMAP00000028890.1; ENSKMAG00000021402.1.
DR   GeneTree; ENSGT00940000164502; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04389; RhoGAP_KIAA1688; 1.
DR   Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR000857; MyTH4_dom.
DR   InterPro; IPR038185; MyTH4_dom_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR45876; FI04035P; 1.
DR   PANTHER; PTHR45876:SF4; ZGC:92107; 1.
DR   Pfam; PF00784; MyTH4; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00139; MyTH4; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51016; MYTH4; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          544..695
FT                   /note="MyTH4"
FT                   /evidence="ECO:0000259|PROSITE:PS51016"
FT   DOMAIN          743..931
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          72..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        171..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..254
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..308
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        431..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   936 AA;  103807 MW;  564A5114D42D0F23 CRC64;
     AAGATDRHIV SHFFFRDASQ RWQPVPGSKA AMLVKVNSMN RSQPNPALQQ QLQPSAQSKA
     SAFTLHNSCD KTQGGHMSSS QAFKTAPSGK MAGDPRQAHL RKASNGSFCL VTSEGSYPSP
     LLHRSHTCTP RPVSPHYGRT APIYDEPVSD SPIYDEPPTD MEIEGAHLYN GQPLSRSTPT
     QSLQKPKLLQ HPGSSHSRHR RNPSSDYSPA GLECIKHMVN VDPKQGHPST SPVPTRASSP
     SSREPGTPGP SSLDKKQTWR ILEATVQRAM EARHSRQSSQ ASQEFPSSTP QATANYQDSG
     YSTGPSPSLR RKTRRRVVAG GGAGGRPGSV GSSGELCALN ERLMAEMREV VSRSNTMREV
     RAGLDPEMGD RTVVPRTRGS AGRCPSREDV SGAARSLKGT GNYGNPALTP LEIPGRQKRT
     YEKVDTLEMS VNSQASLSSP ETPGPPSQVD TLELQSQLES RKKGMVDGRT ASLGPHRSSN
     HDNREGDDGT GSRGGGSSYQ LSYATLRQPP PPDMGMEDWA SKHLNMHTQG LFRRRVSIAN
     MLSWNRGSIK KPMLVTSNRA IRKEACEMFK LVQAYMGDRP SRLDRRHCAL LIVTKCWDMP
     GLRDELYVQL VRQTTGNASP RSLGAGWELM AVSLAFFAPS PKFRCYLEGY IQRHTEPNSD
     KKLTQFILEQ QELKLKKNSK SRKKRKQNTE EEEGLPISTY AKFCHRKLLK VAITGGKKGL
     RKPTLEEIDH SRRAIITPSL FGSSLEEVME RQSELFPDRK LPWVQVQLSQ YVLALGGAQT
     EGIFRVPGDI DEVNALKLQV DQWRIPENLS DPNVPASLMK LWYRELEEPL IPMNFYKQCI
     SNCDDPVAAI AVVQSLPELN RLVLFYFIHF LQVFAQPSNV AITKMDVNNL AMVMAPNCLR
     CQSDDPRVIF ENTRKEMSFL RMLIVHLDTS FIEGVV
//