ID A0A3Q3BMB7_HAPBU Unreviewed; 190 AA.
AC A0A3Q3BMB7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
OS Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000002371.1, ECO:0000313|Proteomes:UP000264840};
RN [1] {ECO:0000313|Ensembl:ENSHBUP00000002371.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR RefSeq; XP_005945013.1; XM_005944951.1.
DR AlphaFoldDB; A0A3Q3BMB7; -.
DR STRING; 8153.ENSHBUP00000002371; -.
DR Ensembl; ENSHBUT00000012209.1; ENSHBUP00000002371.1; ENSHBUG00000003583.1.
DR GeneID; 102303940; -.
DR GeneTree; ENSGT00940000158825; -.
DR OMA; ENPYSEC; -.
DR OrthoDB; 2883843at2759; -.
DR Proteomes; UP000264840; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF31; FIBROBLAST GROWTH FACTOR 4; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Mitogen {ECO:0000256|ARBA:ARBA00023246};
KW Reference proteome {ECO:0000313|Proteomes:UP000264840};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU049442}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT CHAIN 21..190
FT /note="Fibroblast growth factor"
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT /id="PRO_5018382497"
SQ SEQUENCE 190 AA; 21143 MW; 669428849037C4C1 CRC64;
MSSPRSKLPL LLYGILLCSA SAPLPVISRT RQTVRSAGSL VSPSSNIWDK REVTAKDGEY
LLGIKRLRRL YCNVGIGFHI QVLPNGKITG VHNENRYTLL EISPVERGVV TLYGVRSGLF
VAMNDKGKLY GSGHYNDECK FKENILANNY NAYESAAYPG MYIGLSKMGK SKRGNRVTPK
MTMTHFLPRI
//
